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Oesophagitis was a presenting feature in 11 patients and its development was most closely correlated with postprandial reflux, which was characterized by cumulative acid exposure rather than by clearance abnormalities. Upright reflux was not associated with a hypotensive lower oesophageal sphincter or with oesophageal dysmotility. Antireflux surgery is indicated when conservative measures fail and was not associated with gas-bloat syndrome after operation.<\/jats:p>","DOI":"10.1002\/bjs.1800810226","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:08:19Z","timestamp":1172952499000},"page":"239-240","source":"Crossref","is-referenced-by-count":8,"title":["Implications of upright gastro-oesophageal reflux"],"prefix":"10.1093","volume":"81","author":[{"given":"P","family":"Gillen","sequence":"first","affiliation":[{"name":"University Department of Surgery, Trinity College Medical School, St James's Hospital , Dublin,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Thornton","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Trinity College Medical School, St James's Hospital , Dublin,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P J","family":"Byrne","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Trinity College Medical School, St James's Hospital , Dublin,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T N","family":"Walsh","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Trinity College Medical School, St James's Hospital , Dublin,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T P J","family":"Hennessy","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Trinity College Medical School, St James's Hospital , Dublin,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,2,1]]},"reference":[{"key":"2024092814485923600_bib1","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/00000658-197610000-00009","article-title":"Patterns of gastroesophageal reflux in health and disease","volume":"184","author":"DeMeester","year":"1976","journal-title":"Ann Surg"},{"key":"2024092814485923600_bib2","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1136\/gut.28.5.519","article-title":"Daytime gastro-oesophageal reflux is important in oesophagitis","volume":"28","author":"De Caestecker","year":"1987","journal-title":"Gut"},{"key":"2024092814485923600_bib3","first-page":"36","article-title":"Acid reflux and oesophagitis - 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