{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T23:53:36Z","timestamp":1778630016300,"version":"3.51.4"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[1994,3,1]],"date-time":"1994-03-01T00:00:00Z","timestamp":762480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100005983","name":"Dutch Ministry of Trade and Industry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005983","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A neosphincter was successfully created around each end of a Thiry-Vella loop in five dogs using transposed sartorius muscle to study new treatments for faecal incontinence. One of these dynamic neosphincters in each dog was electrically trained for 8 weeks while the other served as a control. Muscle biopsies demonstrated an increase in type 1 fatigue-resistant fibres from a median of 49 (range 37\u201354) per cent before electrical stimulation to 78 (range 53\u201399) per cent 8 weeks later in the stimulated sartorius neosphincters (P&amp;lt;0.05), whereas the percentage of type 1 fibres in control neosphincters increased only slightly.<\/jats:p>\n               <jats:p>Retention times of saline increased from a median of 10 (range 5\u201350) s before to 340 (range 100\u2013470) s after electrical stimulation (P&amp;lt; 0.05) but also increased in control neosphincters (to 370 (range 330\u20131200) s); this may indicate that electrical stimulation immediately increases acute retention times. It is concluded that construction of a neosphincter is technically feasible with preservation of muscle morphology and that stimulation induces morphological and functional changes towards the characteristics of the external anal sphincter.<\/jats:p>","DOI":"10.1002\/bjs.1800810350","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:04:37Z","timestamp":1172952277000},"page":"466-469","source":"Crossref","is-referenced-by-count":13,"title":["Canine model for treatment of faecal incontinence using transposed and electrically stimulated sartorius muscle"],"prefix":"10.1093","volume":"81","author":[{"given":"J","family":"Konsten","sequence":"first","affiliation":[{"name":"Department of Surgery, Maastricht University Hospital , 6202-AZ Maastricht,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C G M I","family":"Baeten","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maastricht University Hospital , 6202-AZ Maastricht,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M G","family":"Havenith","sequence":"additional","affiliation":[{"name":"Department of Pathology, Maastricht University Hospital , 6202-AZ Maastricht,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P B","family":"Soeters","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maastricht University Hospital , 6202-AZ Maastricht,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,3,1]]},"reference":[{"key":"2024092814525858800_bib1","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1097\/00000658-195206000-00010","article-title":"Construction of a rectal sphincter and restoration of anal incontinence by transplanting gracilis muscle: a report of four cases in 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