{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:25:28Z","timestamp":1770823528462,"version":"3.50.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[1994,4,1]],"date-time":"1994-04-01T00:00:00Z","timestamp":765158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Occasionally pancreatoduodenectomy is performed for clinically suspected pancreatic malignancy only for the surgeon to find that a benign aetiology accounts for the pancreatic mass. The aim of this study was twofold: to determine the incidence of pancreatoduodenectomy performed for a misdiagnosis of pancreatoduodenal malignancy and to identify potentially avoidable errors in preoperative and intraoperative judgement. Between 1956 and 1990, radical pancreatoduodenectomy was performed in 603 patients at the Mayo Clinic; 29 (5 per cent) underwent pancreatoduodenectomy for a diagnosis made before and during surgery of primary pancreatic or periampullary malignancy that was later proven histopathologically to be either unsuspected subacute or chronic pancreatitis (22 patients), benign fibrous common bile duct stricture (two), and penetrating duodenal ulcer, metastatic melanoma, ampullary adenoma, intrahepatic drug-induced cholestasis and pseudocyst (one each). No patient had a preoperative diagnosis of chronic pancreatitis. Weight loss, pain and\/or jaundice were present in 27 of the 29 patients. Objective imaging tests, such as computed tomography, ultrasonography and\/or endoscopic retrograde cholangio-pancreatography, were performed in 25 patients. Potential errors in judgement may be avoided by a more aggressive attempt at biopsy in selected patients; in others, resection for presumed malignancy may be unavoidable.<\/jats:p>","DOI":"10.1002\/bjs.1800810435","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:46:22Z","timestamp":1172954782000},"page":"585-589","source":"Crossref","is-referenced-by-count":103,"title":["Radical pancreatoduodenectomy for misdiagnosed pancreatic mass"],"prefix":"10.1093","volume":"81","author":[{"given":"C D","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Surgery, Mayo Clinic and Mayo Foundation , Rochester, Minnesota,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K E","family":"Behrns","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic and Mayo Foundation , Rochester, Minnesota,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J A","family":"Van Heerden","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic and Mayo Foundation , Rochester, Minnesota,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M G","family":"Sarr","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mayo Clinic and Mayo Foundation , Rochester, Minnesota,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,4,1]]},"reference":[{"key":"2024092814500155400_bib1","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/0016-5085(83)90371-2","article-title":"A blinded prospective study comparing four current noninvasive approaches in the differential diagnosis of medical versus surgical jaundice","volume":"84","author":"O'Connor","year":"1983","journal-title":"Gastroenterology"},{"key":"2024092814500155400_bib2","first-page":"637","volume-title":"Disease of the Liver","author":"Zimmerman","year":"1987","edition":"6th"},{"key":"2024092814500155400_bib3","first-page":"595","article-title":"Metastatic melanoma: an unusual cause of obstructive jaundice","volume":"107","author":"England","year":"1990","journal-title":"Surgery"},{"key":"2024092814500155400_bib4","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1097\/00000658-198709000-00014","article-title":"Improved hospital morbidity, mortality, and survival after the Whipple procedure","volume":"206","author":"Crist","year":"1987","journal-title":"Ann Surg"},{"key":"2024092814500155400_bib5","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1001\/archsurg.1989.01410070028006","article-title":"An analysis of the reduced morbidity and mortality rates after pancreaticoduodenectomy","volume":"124","author":"Pellegrini","year":"1989","journal-title":"Arch Surg"},{"key":"2024092814500155400_bib6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/00000658-198801000-00009","article-title":"The complications of pancreatectomy","volume":"207","author":"Trede","year":"1988","journal-title":"Ann Surg"},{"key":"2024092814500155400_bib7","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1007\/BF01656028","article-title":"Pancreatic resection for carcinoma of the pancreas: Whipple versus total pancreatectomy - an institutional perspective","volume":"8","author":"van Heerden","year":"1984","journal-title":"World J Surg"},{"key":"2024092814500155400_bib8","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1097\/00000658-199004000-00011","article-title":"Survival after pancreatoduodenectomy: 118 consecutive resections without an operative mortality","volume":"211","author":"Trede","year":"1990","journal-title":"Ann Surg"},{"key":"2024092814500155400_bib9","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1001\/archsurg.1992.01420080079012","article-title":"Complications following pancreaticoduodenectomy: current management","volume":"127","author":"Miedema","year":"1992","journal-title":"Arch Surg"},{"key":"2024092814500155400_bib10","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1002\/1097-0142(19820301)49:5<1035::AID-CNCR2820490530>3.0.CO;2-1","article-title":"Tissue diagnosis for carcinoma of the pancreas and periampullary structures","volume":"49","author":"Lee","year":"1982","journal-title":"Cancer"},{"key":"2024092814500155400_bib11","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/00000658-198601000-00013","article-title":"Collective review of small carcinomas of the pancreas","volume":"203","author":"Tsuchiya","year":"1986","journal-title":"Ann Surg"},{"key":"2024092814500155400_bib12","first-page":"602","article-title":"Cancer of the head of the pancreas or chronic pancreatitis? 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