{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:47:23Z","timestamp":1761630443690,"version":"3.37.3"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[1994,7,1]],"date-time":"1994-07-01T00:00:00Z","timestamp":773020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Royal Victoria Hospital Belfast"},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation and Department of Health and Social Services Board of Northern Ireland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In 30 patients undergoing elective repair of abdominal aortic aneurysm the intramucosal pH (pHi) of the sigmoid colon was measured. Blood for endotoxin assay was taken at intervals before, during and after surgery. Daily measurements were made of liver transaminase activity and of arterial partial pressure of oxygen (PaO2). The mean(s.e.m.) peak systemic endotoxin concentration in those who developed intramucosal acidosis (pHi below 7\u00b700) was 90(14) pg\/ml, compared with 42(5) pg\/ml in those who did not (P &amp;lt; 0\u00b701). In the 14 patients whose pHi fell below 7\u00b700, the mean(s.e.m.) postoperative rise in aspartate transaminase activity was 346(74) per cent, compared with 181(20) per cent in those whose pHi remained above this level (P &amp;lt; 0\u00b705). The mean(s.e.m.) postoperative ratio of PaO2, to the fraction of inspired oxygen was 177(11) mmHg in those with intramucosal acidosis, compared with 260(24) mmHg in those whose pHi remained above 7\u00b700 (P &amp;lt; 0\u00b701). These results demonstrate a relationship between bowel ischaemia, endotoxaemia and organ impairment following elective aneurysm repair.<\/jats:p>","DOI":"10.1002\/bjs.1800810712","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:26:35Z","timestamp":1172953595000},"page":"965-968","source":"Crossref","is-referenced-by-count":72,"title":["Bowel ischaemia and organ impairment in elective abdominal aortic aneurysm repair"],"prefix":"10.1093","volume":"81","author":[{"given":"C V","family":"Soong","sequence":"first","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Belfast,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P H B","family":"Blair","sequence":"additional","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Belfast,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M I","family":"Halliday","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Queen's University of Belfast , Belfast,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M D","family":"McCaigue","sequence":"additional","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Belfast,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Hood","sequence":"additional","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Belfast,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B J","family":"Rowlands","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Queen's University of Belfast , Belfast,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A A B","family":"Barrosd'sa","sequence":"additional","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Belfast,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,7,1]]},"reference":[{"key":"2024102821424702700_bib1","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/ageing\/11.4.256","article-title":"Time and cause of death for 301 patients operated on for abdominal aortic aneurysms","volume":"11","author":"Soreide","year":"1982","journal-title":"Age Ageing"},{"key":"2024102821424702700_bib2","first-page":"275","article-title":"The mortality of abdominal aortic aneurysm","volume":"68","author":"Campbell","year":"1986","journal-title":"Ann R Coll Surg Engl"},{"key":"2024102821424702700_bib3","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1097\/00003246-198709000-00007","article-title":"Transient episodes of sigmoid ischemia and their relation to infection from intestinal organisms after abdominal aortic operations","volume":"15","author":"Fiddian-Green","year":"1987","journal-title":"Crit Care Med"},{"key":"2024102821424702700_bib4","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1001\/archsurg.1986.01400060048005","article-title":"Prediction of the development of sigmoid ischemia on the day of aortic operations. 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