{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:21:08Z","timestamp":1740126068810,"version":"3.37.3"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[1994,7,1]],"date-time":"1994-07-01T00:00:00Z","timestamp":773020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100006310","name":"Swedish Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The completeness of vagal denervation in determining the long\u2013term outcome of patients with duodenal ulcer disease after proximal gastric vagotomy (PGV) was studied by examining the relationship between the postoperative acid secretory response to sham feeding (\u2018chew and spit\u2019 technique) and the subsequent ulcer recurrence rate during a mean follow-up of 7\u00b75 (range 5\u201315) years. The cumulative recurrence rate of 98 patients analysed prospectively was 11 per cent Of 22 patients who had incomplete vagotomy as suggested by the sham feeding response, five had a later relapse. This compares with only an 8 per cent relapse rate among those with a secretory response suggesting complete vagotomy. Four patients suffered from a relapse more than 5 years after operation but none had undergone incomplete vagotomy. However, in seven patients with an early postoperative relapse (within 5 years) five had had incomplete vagal denervation (P &amp;lt; 0\u00b705). In this latter group the median time elapsed from surgery until the first recurrence was only 1 year. It is concluded that the early postoperative acid secretory response to a sham feeding stimulus is clinically useful as it allows prediction of the risk of early relapse after PGV. This test may be helpful for the validation of new techniques of vagotomy.<\/jats:p>","DOI":"10.1002\/bjs.1800810724","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:26:35Z","timestamp":1172953595000},"page":"1002-1006","source":"Crossref","is-referenced-by-count":2,"title":["Role of acid secretory response to sham feeding in predicting recurrent ulceration after proximal gastric vagotomy"],"prefix":"10.1093","volume":"81","author":[{"given":"B","family":"Stenquist","sequence":"first","affiliation":[{"name":"Department of Surgery, Sahlgren Hospital, University of Gothenburg , S-413 45 Gothenburg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Forssell","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sahlgren Hospital, University of Gothenburg , S-413 45 Gothenburg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Olbe","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sahlgren Hospital, University of Gothenburg , S-413 45 Gothenburg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Lundell","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sahlgren Hospital, University of Gothenburg , S-413 45 Gothenburg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,7,1]]},"reference":[{"key":"2024092815142412400_bib1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S0016-5085(19)33704-7","article-title":"Selective vagotomy of the parietal cell mass preserving innervation of the undrained antrum: a preliminary report of results in patients with duodenal 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