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Group 1 comprised three children with idiopathic intrahepatic portal vein occlusion alone (hepatoportal sclerosis). Those in group 2 (25 patients), with occlusion of the main portal vein, accounted for almost half the total number and for most of those with a probable congenital aetiology. The ten patients in group 3 had angiographic occlusion and collateralization of the main portal and superior mesenteric veins. Intra-abdominal sepsis, other than that from pancreatic disease, was associated with this pattern of venous occlusion in which the splenic vein is spared. No patients with isolated portal and splenic vein occlusion (group 4) were recorded. Widespread thrombosis throughout the portal venous system (group 5; 15 patients) had a multifactorial aetiology but was typically observed in hypercoagulable states that were also associated with hepatic vein occlusion or other deep vein thromboses.<\/jats:p>","DOI":"10.1002\/bjs.1800810923","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:54:15Z","timestamp":1172955255000},"page":"1328-1331","source":"Crossref","is-referenced-by-count":35,"title":["Patterns of portal vein occlusion and their aetiological significance"],"prefix":"10.1093","volume":"81","author":[{"given":"M D","family":"Stringer","sequence":"first","affiliation":[{"name":"Department of Surgery, King's College Hospital , Denmark Hill, London SE5 9RS,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N D","family":"Heaton","sequence":"additional","affiliation":[{"name":"Department of Surgery, King's College Hospital , Denmark Hill, London SE5 9RS,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Karani","sequence":"additional","affiliation":[{"name":"Department of Surgery, King's College Hospital , Denmark Hill, London SE5 9RS,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Olliff","sequence":"additional","affiliation":[{"name":"Department of Radiology, King's College Hospital , Denmark Hill, London SE5 9RS,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E R","family":"Howard","sequence":"additional","affiliation":[{"name":"Department of Surgery, King's College Hospital , Denmark Hill, London SE5 9RS,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,9,1]]},"reference":[{"key":"2024092815074441100_bib1","first-page":"26","volume-title":"Surgery of Liver Disease in Children","author":"Pain","year":"1991"},{"key":"2024092815074441100_bib2","first-page":"465","article-title":"The aetiology of portal vein thrombosis with particular reference to the role of infection and exchange transfusion","volume":"132","author":"Thompson","year":"1964","journal-title":"Q J Med"},{"key":"2024092815074441100_bib3","first-page":"627","article-title":"The aetiology, presentation and natural history of extra-hepatic portal venous obstruction","volume":"192","author":"Webb","year":"1979","journal-title":"Q J Med"},{"key":"2024092815074441100_bib4","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/BF01300098","article-title":"Abdominal tuberculosis - a cause of portal vein thrombosis and portal hypertension","volume":"36","author":"Ruttenberg","year":"1991","journal-title":"Dig Dis Sci"},{"key":"2024092815074441100_bib5","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1001\/archsurg.1970.01340230089024","article-title":"Isolated splenic vein occlusion","volume":"100","author":"Sutton","year":"1970","journal-title":"Arch Surg"},{"key":"2024092815074441100_bib6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/gut.34.1.7","article-title":"Complications and limitations of injection sclerotherapy in portal hypertension","volume":"34","author":"Heaton","year":"1993","journal-title":"Gut"},{"key":"2024092815074441100_bib7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2214\/ajr.112.1.143","article-title":"Extrahepatic portal obstruction in childhood and its angiographic diagnosis","volume":"112","author":"Rosch","year":"1971","journal-title":"AJR Am J Roentgenol"},{"key":"2024092815074441100_bib8","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/00000658-198007000-00003","article-title":"Portal diversion for portal hypertension in children","volume":"192","author":"Bismuth","year":"1980","journal-title":"Ann Surg"},{"key":"2024092815074441100_bib9","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S0022-3476(83)80460-0","article-title":"Portal obstruction in children. 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