{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:14:52Z","timestamp":1790766892770,"version":"4.1.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[1994,9,1]],"date-time":"1994-09-01T00:00:00Z","timestamp":778377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Persistent symptoms after cholecystectomy are common, occurring in up to 40 per cent of patients. Severe pain persists in 10 per cent of cases. A total of 450 patients were studied, 200 after open cholecystectomy and 250 after the laparoscopic operation. Patient notes were reviewed and a postal questionnaire was circulated. Responses were obtained from 155 patients (77\u00b75 per cent) undergoing opencholecystectomy and 205 (82\u00b70 per cent) having the laparoscopic operation. Mean(s.d.) follow-up was 32(23) months after open cholecystectomy and 15(7) months after the laparoscopic procedure. Right upper quadrant pain was more common after open cholecystectomy (9\u00b77 versus 3\u00b74 per cent, P &amp;lt; 0\u00b705). Indigestion and heartburn were equally prevalent in the two groups. Some 59\u00b74 per cent of patients were free from symptoms after open cholecystectomy compared with 63\u00b74 per cent following the laparoscopic operation; there was symptomatic improvement in 30\u00b73 and 31\u00b77 per cent respectively. Symptoms were the same or worse in 10\u00b73 per cent of patients after open cholecystectomy compared with 4\u00b79 per cent after the laparoscopic operation (P &amp;lt; 0\u00b705). Patients report significantly less right upper quadrant pain after laparoscopic than after open cholecystectomy.<\/jats:p>","DOI":"10.1002\/bjs.1800810939","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:54:15Z","timestamp":1172955255000},"page":"1368-1370","source":"Crossref","is-referenced-by-count":68,"title":["Long-term pain: Less common after laparoscopic than open cholecystectomy"],"prefix":"10.1093","volume":"81","author":[{"given":"G","family":"Stiff","sequence":"first","affiliation":[{"name":"Department of Surgery, University Hospital of Wales , Cardiff,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Rhodes","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital of Wales , Cardiff,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Surgery, Frenchay Hospital , Bristol,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Telford","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital of Wales , Cardiff,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C P","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Department of Surgery, Frenchay Hospital , Bristol,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B I","family":"Rees","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital of Wales , Cardiff,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1994,9,1]]},"reference":[{"key":"2024092815373427200_bib1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0300-5089(21)00336-9","article-title":"The postcholecystectomy syndromes","volume":"2","author":"Bodvall","year":"1973","journal-title":"Clin Gastroenterol"},{"key":"2024092815373427200_bib2","first-page":"1175","article-title":"Confidence bounds for the difference between two probabilities","volume":"40","author":"Mee","year":"1984","journal-title":"Biometrics"},{"key":"2024092815373427200_bib3","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1136\/gut.28.11.1500","article-title":"Postcholecystectomy symptoms. 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A prospective analysis of 100 initial patients","volume":"213","author":"Peters","year":"1991","journal-title":"Ann Surg"},{"key":"2024092815373427200_bib8","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1136\/gut.34.10.1448","article-title":"Outcome after cholecystectomy for symptomatic gall stone disease and effect of surgical access: laparoscopic v open approach","volume":"34","author":"Vander","year":"1993","journal-title":"Gut"},{"key":"2024092815373427200_bib9","first-page":"296","volume-title":"Surgical Treatment of Digestive Disease","author":"Moody","year":"1986"},{"key":"2024092815373427200_bib10","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0002-9610(91)90603-B","article-title":"The European experience with laparoscopic cholecystectomy","volume":"161","author":"Cuschieri","year":"1991","journal-title":"Am J Surg"},{"key":"2024092815373427200_bib11","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1001\/jama.1961.63040260007008","article-title":"Surgery as placebo. 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