{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T14:02:00Z","timestamp":1783605720420,"version":"3.55.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[1994,9,1]],"date-time":"1994-09-01T00:00:00Z","timestamp":778377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Anorectal physiology and continence were assessed prospectively before and after surgery in 50 patients with chronic perianal sepsis. Functional and physiological parameters were unchanged after surgery in 13 control patients who had sepsis but who did not undergo division of the anal sphincter. Group 1 comprised 22 patients with internal sphincter division alone (15 intersphincteric, seven trans-sphincteric treated by a loose seton technique) and group 2 consisted of 15 patients with a trans-sphincteric fistula laid completely open. In group 1 the median (interquartile range (i.q.r.)) resting pressure in the distal 1 cm of the anal canal was reduced from 68 (60\u201390) cmH2O before surgery to 44(35\u201360) cmH2O after operation (P&amp;lt;0\u00b7001); squeeze pressure was less affected, but function deteriorated in 11 of the 22 patients. The median (i.q.r.) resting pressure in group 2 patients also fell, from 68(34\u201384) cmH2O before operation to 28 (20\u201354) cmH2O afterwards (P = 0\u00b7003); median (i.q.r.) maximum squeeze pressure decreased more, from 124(76\u2013170) cmH2O to 72 (48\u2013112) cmH2O (P=0\u00b7002). Functional deficit occurred in eight of the 15 patients. Incontinence was related to low resting pressure, reflecting internal sphincter integrity, and to local epithelial electrosensitivity (reflecting scarring), but not to squeeze pressure, fistula type or surgical treatment.<\/jats:p>","DOI":"10.1002\/bjs.1800810947","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T20:54:15Z","timestamp":1172955255000},"page":"1382-1385","source":"Crossref","is-referenced-by-count":162,"title":["Factors affecting continence after surgery for anal fistula"],"prefix":"10.1093","volume":"81","author":[{"given":"P J","family":"Lunniss","sequence":"first","affiliation":[{"name":"Department of Surgery, St Bartholomew's and St Mark's Hospitals , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M A","family":"Kamm","sequence":"additional","affiliation":[{"name":"Sir Alan Parks Physiology Unit, St Mark's Hospital , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R K S","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Surgery, St Bartholomew's and St Mark's Hospitals , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1994,9,1]]},"reference":[{"key":"2024092815152833200_bib1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1002\/bjs.1800760628","article-title":"Anorectal physiology validated: a repeatability study of the motor and sensory tests of anorectal function","volume":"76","author":"Rogers","year":"1989","journal-title":"Br J Surg"},{"key":"2024092815152833200_bib2","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/bjs.1800730421","article-title":"New method for assessment of anal sensation in various anorectal disorders","volume":"73","author":"Roe","year":"1986","journal-title":"Br J Surg"},{"key":"2024092815152833200_bib3","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/bjs.1800710817","article-title":"Slowed conduction in the pudendal nerves in idiopathic (neurogenic) faecal incontinence","volume":"71","author":"Kiff","year":"1984","journal-title":"Br J Surg"},{"key":"2024092815152833200_bib4","first-page":"355","article-title":"Investigation of disorders of the anorectum and colon","volume":"67","author":"Henry","year":"1985","journal-title":"Ann R Coll Surg Engl"},{"key":"2024092815152833200_bib5","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/BF02156270","article-title":"Rectal mucosal electrosensitivity testing - evidence for a rectal sensory neuropathy in idiopathic constipation","volume":"33","author":"Kamm","year":"1990","journal-title":"Dis Colon Rectum"},{"key":"2024092815152833200_bib6","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1002\/bjs.1800690813","article-title":"The pelvic floor musculature in the descending perineum syndrome","volume":"69","author":"Henry","year":"1982","journal-title":"Br J Surg"},{"key":"2024092815152833200_bib7","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF01644991","article-title":"Can the external sphincter be preserved in the treatment of trans-sphincteric fistula-in-ano?","volume":"4","author":"Thomson","year":"1989","journal-title":"Int J Colorectal Dis"},{"key":"2024092815152833200_bib8","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/BF02049407","article-title":"New grading and scoring for anal incontinence. 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