{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:03:47Z","timestamp":1790114627551,"version":"4.0.1"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1995,1,1]],"date-time":"1995-01-01T00:00:00Z","timestamp":788918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100001698","name":"ICRF Colorectal Unit, St. Mark's Hospital, London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001698","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Anal fistulas may fail to heal because of continuing disease within the intersphincteric anal glands. Histological studies of the intersphincteric component of 18 consecutive idiopathic anal fistulas show that fistula persistence may be caused by epithelialization of the fistula track from internal or external openings. Some fistulas are lined by epithelium similar to that of anal gland ducts, but this may also represent epithelium derived from the transitional zone of the anal canal. Persistence may be related more to nonspecific epithelialization of the track than to a chronically infected anal gland.<\/jats:p>","DOI":"10.1002\/bjs.1800820112","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T21:21:21Z","timestamp":1172956881000},"page":"32-33","source":"Crossref","is-referenced-by-count":69,"title":["Persistence of idiopathic anal fistula may be related to epithelialization"],"prefix":"10.1093","volume":"82","author":[{"given":"P J","family":"Lunniss","sequence":"first","affiliation":[{"name":"Department of Surgery, St Bartholomew's Hospital , London EC1V 2PS,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J P","family":"Sheffield","sequence":"additional","affiliation":[{"name":"Department of Histopathology , London EC1V 2PS,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I C","family":"Talbot","sequence":"additional","affiliation":[{"name":"Department of Histopathology , London EC1V 2PS,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J P S","family":"Thomson","sequence":"additional","affiliation":[{"name":"Department of Surgery, St Mark's Hospital , City Road, London EC1V 2PS,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R K S","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Surgery, St Mark's Hospital , City Road, London EC1V 2PS,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1995,1,1]]},"reference":[{"key":"2024092815112794700_bib1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1136\/bmj.1.5224.463","article-title":"The pathogenesis and treatment of fistula-In-ano","volume":"1","author":"Parks","year":"1961","journal-title":"BMJ"},{"key":"2024092815112794700_bib2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/bjs.1800790107","article-title":"Bacteriology of anal fistulae","volume":"79","author":"Seow-Choen","year":"1992","journal-title":"Br J Surg"},{"key":"2024092815112794700_bib3","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1002\/bjs.1800800853","article-title":"Histological and microbiological assessment of the role of microorganisms in chronic anal fistula","volume":"80","author":"Lunniss","year":"1993","journal-title":"Br J Surg"},{"key":"2024092815112794700_bib4","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1007\/BF02049991","article-title":"Anatomic nature and surgical significance of anal sinus and anal intramuscular glands","volume":"34","author":"Klosterhalfen","year":"1991","journal-title":"Dis Colon Rectum"},{"key":"2024092815112794700_bib5","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/bjs.1800228808","article-title":"Observations on fistula in ano in relation to perianal intermuscular glands with reports on 3 cases","volume":"22","author":"Gordon-Watson","year":"1935","journal-title":"Br J Surg"},{"key":"2024092815112794700_bib6","first-page":"116","volume-title":"Bailey and Love's Short Practice of Surgery","author":"Harding","year":"1988","edition":"20th"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800820112","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/82\/1\/32\/59412387\/bjs1800820112.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/82\/1\/32\/59412387\/bjs1800820112.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T15:11:33Z","timestamp":1727536293000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/82\/1\/32\/6165986"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1,1]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1995,1,1]]},"published-print":{"date-parts":[[1995,1,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800820112","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1995,1]]},"published":{"date-parts":[[1995,1,1]]}}}