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There are two groups of mammary cysts: those lined by apocrine epithelium (intracystic sodium to potassium (Na:K) ratio &amp;lt; 3) and those lined by flattened epithelium (intracystic Na:K ratio &amp;gt; 3). Cell adhesion molecules may be involved in various stages of tumour metastasis. Intracystic levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) and soluble E-selectin (sE-selectin) were measured. Significantly greater concentrations of sVCAM-1 and sE-selectin occurred in the high-electrolyte ratio group than in the low (P &amp;lt;0\u00b7001). A positive correlation was found between sVCAM-1 and sE-selectin (rS = 0\u00b7827, P &amp;lt;0\u00b7001) which may be a chance observation or suggest a common mechanism of entry into mammary cysts. The significance of these soluble cell adhesion molecules in breast cyst fluid requires elucidation.<\/jats:p>","DOI":"10.1002\/bjs.1800820129","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T21:21:21Z","timestamp":1172956881000},"page":"83-85","source":"Crossref","is-referenced-by-count":4,"title":["Concentrations of soluble vascular cell adhesion molecule-1 and E-selectin in breast cyst fluid and their relation with cyst type"],"prefix":"10.1093","volume":"82","author":[{"given":"L C","family":"Lai","sequence":"first","affiliation":[{"name":"Department of Clinical Biochemistry, Freeman Group of Hospitals NHS Trust , Freeman Road, Newcastle upon Tyne, NE7 7DN,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A K","family":"Siraj","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Freeman Group of Hospitals NHS Trust , Freeman Road, Newcastle upon Tyne, NE7 7DN,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kadory","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Freeman Group of Hospitals NHS Trust , Freeman Road, Newcastle upon Tyne, NE7 7DN,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T W J","family":"Lennard","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Medical School, University of Newcastle upon Tyne , Newcastle upon Tyne, NE2 4HH,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1995,1,1]]},"reference":[{"volume-title":"Breast Carcinoma, Risk and Detection","year":"1981","author":"Haagensen","key":"2024092815130480200_bib1"},{"key":"2024092815130480200_bib2","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/0277-5379(90)90074-4","article-title":"Risk of breast cancer subsequent to proven gross cystic disease","volume":"26","author":"Ciatto","year":"1990","journal-title":"Eur J Cancer"},{"key":"2024092815130480200_bib3","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1056\/NEJM198501173120303","article-title":"Risk factors for breast cancer in women with proliferative breast disease","volume":"312","author":"Dupont","year":"1985","journal-title":"N Engl J Med"},{"key":"2024092815130480200_bib4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1749-6632.1990.tb17800.x","article-title":"Epidermal growth factor in breast cyst fluids. 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