{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T14:44:32Z","timestamp":1772030672818,"version":"3.50.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[1995,2,1]],"date-time":"1995-02-01T00:00:00Z","timestamp":791596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>As part of a continuing audit of patients undergoing laparoscopic cholecystectomy (which now numbers over 1500) 468 of the 508 patients (92\u00b71 per cent) operated on between October 1989 and March 1991 were studied between 350 and 988 days after the operation (mean 19 months). A questionnaire was filled in by each patient before operation and at the late follow-up visit. Eight specific symptoms were sought - non-colicky pain, colic, abdominal distension, nausea, vomiting, loss of appetite, flatulence, and dietary restriction. The result of each operation was assessed by two surgeons and by the patient. In 453 patients (96\u00b78 per cent) the symptoms had improved as a result of the operation, but 260 patients (55\u00b76 per cent) had some abdominal symptoms. The result was assessed as excellent in 310 patients (66\u00b72 per cent); 143 (30\u00b75 per cent) still had abdominal complaints but they were willing to cope with those symptoms. In 15 patients (3\u00b72 per cent) the result was unsatisfactory. Statistical analysis of 26 preoperative variables showed few significant differences between patients with excellent results and patients with persisting or new symptoms. The percentage of patients with biliary colic was reduced from 82\u00b79 per cent before to 6\u00b74 per cent after laparoscopic cholecystectomy (P &amp;lt;0\u00b705), and of those with flatulence from 62\u00b76 per cent to 45\u00b73 per cent (P &amp;lt;0\u00b705). Flatulence persisted in 147 (50\u00b72 per cent) of the 293 patients who had complained of flatulence before the operation, and of the 175 patients who had not complained of flatulence before surgery, 65 (37\u00b71 per cent) reported the symptom for the first time after the operation. It appears that \u2018flatulent dyspepsia\u2019 after cholecystectomy has many causes, one of which may be removal of the gallbladder. It is concluded that the long-term results of laparoscopic cholecystectomy in patients with symptomatic gallstone disease were excellent but the prognosis in individual patients was unpredictable.<\/jats:p>","DOI":"10.1002\/bjs.1800820243","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T21:37:25Z","timestamp":1172957845000},"page":"267-270","source":"Crossref","is-referenced-by-count":42,"title":["Long-term results after laparoscopic cholecystectomy"],"prefix":"10.1093","volume":"82","author":[{"given":"B M","family":"Ure","sequence":"first","affiliation":[{"name":"Surgical Clinic, University of Cologne , Koln,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Troidl","sequence":"additional","affiliation":[{"name":"Surgical Clinic, University of Cologne , Koln,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W","family":"Spangenberger","sequence":"additional","affiliation":[{"name":"Surgical Clinic, University of Cologne , Koln,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Lefering","sequence":"additional","affiliation":[{"name":"Biochemical and Experimental Division of the II Department of Surgery, University of Cologne , Koln,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Dietrich","sequence":"additional","affiliation":[{"name":"Biochemical and Experimental Division of the II Department of Surgery, University of Cologne , Koln,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E P","family":"Eypasch","sequence":"additional","affiliation":[{"name":"Surgical Clinic, University of Cologne , Koln,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Neugebauer","sequence":"additional","affiliation":[{"name":"Biochemical and Experimental Division of the II Department of Surgery, University of Cologne , Koln,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1995,2,1]]},"reference":[{"key":"2024092814463525000_bib1","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1007\/BF02067064","article-title":"Laparoscopic cholecystectomy: the state of the art. 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