{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T12:54:14Z","timestamp":1787144054927,"version":"build-2736575974"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[1995,7,1]],"date-time":"1995-07-01T00:00:00Z","timestamp":804556800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The effect of low-dose dopamine administration on intramucosal pH (pHi) of the sigmoid colon and on postoperative function of various organs in patients undergoing elective abdominal aortic aneurysm repair was examined. Nineteen patients were randomized to two groups; nine received dopamine at a rate of 3 \u03bcg per kg per min for 24 h from induction of anaesthesia and ten control patients received fluids without dopamine. pHi was measured with a silicone tonometer and daily samples of blood were taken for measurement of liver transaminase activity, arterial oxygen saturation and creatinine concentration. Mean(s.e.m.) pHi fell to a significantly lower minimum value in those receiving dopamine compared with control patients (6.86(0.10) versus 7.11(0.08), P&amp;lt;0.05). Five of the nine patients given dopamine developed intramucosal acidosis compared with only one of the ten control patients (P = 0.06). After operation the mean(s.e.m.) aspartate transminase concentration in patients given dopamine rose from 33(2) to 80(17) units\/1 (P&amp;lt;0.01); in control patients it rose from 32(3) to 59(16) units\/1 (P = 0.054). No difference between the groups was observed in the postoperative ratio of arterial oxygen saturation to inspired oxygen fraction or creatinine conceritrations. These results indicate that dopamine has no beneficial effect on bowel mucosal oxygenation and function of the various organs in patients undergoing aortic aneurysm repair.<\/jats:p>","DOI":"10.1002\/bjs.1800820718","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T22:37:27Z","timestamp":1172961447000},"page":"912-915","source":"Crossref","is-referenced-by-count":13,"title":["Effect of low-dose dopamine on sigmoid colonic intramucosal pH in patients undergoing elective abdominal aortic aneurysm repair"],"prefix":"10.1093","volume":"82","author":[{"given":"C V","family":"Soong","sequence":"first","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Grosvenor Road, Belfast BT12 6BJ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M I","family":"Halliday","sequence":"additional","affiliation":[{"name":"Department of Surgery, Queen's University , Grosvenor Road, Belfast BT12 6BJ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J M","family":"Hood","sequence":"additional","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Grosvenor Road, Belfast BT12 6BJ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B J","family":"Rowlands","sequence":"additional","affiliation":[{"name":"Department of Surgery, Queen's University , Grosvenor Road, Belfast BT12 6BJ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A A B","family":"Barros D'Sa","sequence":"additional","affiliation":[{"name":"Vascular Surgery Unit, Royal Victoria Hospital , Grosvenor Road, Belfast BT12 6BJ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1995,7,1]]},"reference":[{"key":"2024092816191340800_bib1","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1097\/00003246-198709000-00007","article-title":"Transient episodes of sigmoid ischemia and their relation to infection from intestinal organisms after abdominal aortic operations","volume":"15","author":"Fiddian-Green","year":"1987","journal-title":"Crit Care Med"},{"key":"2024092816191340800_bib2","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1001\/archsurg.1986.01400060048005","article-title":"Prediction of the development of sigmoid ischemia on the day of aortic operations. 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