{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:35:47Z","timestamp":1792146947589,"version":"4.4.0"},"reference-count":147,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[1995,8,1]],"date-time":"1995-08-01T00:00:00Z","timestamp":807235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Budd-Chiari syndrome is the generic term for different forms of hepatic venous outflow obstruction resulting in a clinical picture of portal hypertension and hepatomegaly. Three levels of venous outflow obstruction may be recognized, affecting respectively the small intrahepatic venules, the large hepatic veins and the inferior vena cava (IVC). Each level of obstruction is related to a different aetiology. Clinical manifestations range from mild symptoms to acute or chronic end-stage liver disease. Treatment is surgical in the great majority of patient Occlusion of the IVC may be treated by removal of the caval obstruction in selected patients. Hepatic outflo obstruction may be circumvented by different forms of shunting from the portal or upper mesenteric vein to the IVC or right atrium, depending on the level of obstruction and the difference in venous pressure. For the rare patient presenting with acute or chronic end-stage liver failure hepatic transplantation may be a life-saving procedure.<\/jats:p>","DOI":"10.1002\/bjs.1800820807","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T22:38:11Z","timestamp":1172961491000},"page":"1023-1030","source":"Crossref","is-referenced-by-count":44,"title":["Budd-Chiari syndrome"],"prefix":"10.1093","volume":"82","author":[{"given":"H W","family":"Tilanus","sequence":"first","affiliation":[{"name":"Department of Surgery, Erasmus University Hospital \u2018Dijkzigt\u2019 , Dr Molewaterplein 40, 3015-GD Rotterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1995,8,1]]},"reference":[{"key":"2024092816220323400_bib1","first-page":"146","volume-title":"On Diseases of the Liver","author":"Budd","year":"1845","edition":"1st"},{"key":"2024092816220323400_bib2","first-page":"1","article-title":"Ueber die Selbst\u00e4ndige Phlebitis Obliterans der Hauptstamme der Venae Hepaticae als Todesursache","volume":"26","author":"Chiari","year":"1899","journal-title":"Beitr Pathol"},{"key":"2024092816220323400_bib3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0025-6196(12)62109-0","article-title":"Classification of hepatic venous outflow obstruction: ambiguous terminology of the Budd-Chiari syndrome","volume":"65","author":"Ludwig","year":"1990","journal-title":"Mayo Clin Proc"},{"key":"2024092816220323400_bib4","first-page":"291","article-title":"Veno-occlusive disease of the liver","volume":"26","author":"Stuart","year":"1957","journal-title":"Q J Med"},{"key":"2024092816220323400_bib5","first-page":"201","article-title":"Pyrrolizidine alkaloids","volume":"i","author":"Editorial","year":"1984","journal-title":"Lancet"},{"key":"2024092816220323400_bib6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0002-9343(89)80492-9","article-title":"Comfrey herb tea-induced hepatic veno-occlusive disease","volume":"87","author":"Bach","year":"1989","journal-title":"Am J Med"},{"key":"2024092816220323400_bib7","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/S0140-6736(83)91112-1","article-title":"Hepatic veno-occlusive disease due to toxic alkaloid herbal tea","volume":"ii","author":"Kumana","year":"1983","journal-title":"Lancet"},{"key":"2024092816220323400_bib8","first-page":"285","article-title":"Veno-occlusive disease of the liver with non-portal type of cirrhosis, occurring in Jamaica","volume":"57","author":"Bras","year":"1954","journal-title":"A M A Arch Pathol"},{"key":"2024092816220323400_bib9","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0002-9343(86)90266-4","article-title":"Hepatic vein-occlusive disease","volume":"86","author":"Rollins","year":"1986","journal-title":"Am J Med"},{"key":"2024092816220323400_bib10","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/hep.1840040121","article-title":"Veno-occlusive disease of the liver after bone marrow transplantation: diagnosis, incidence, and predisposing factors","volume":"4","author":"McDonald","year":"1984","journal-title":"Hepatology"},{"key":"2024092816220323400_bib11","doi-asserted-by":"crossref","first-page":"651","DOI":"10.7326\/0003-4819-104-5-651","article-title":"Hepatic veno-occlusive disease associated with renal transplantation and azathioprine therapy","volume":"104","author":"Read","year":"1986","journal-title":"Ann Intern Med"},{"key":"2024092816220323400_bib12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.7326\/0003-4819-103-3-329","article-title":"Primary myeloproliferative disorder and hepatic vein thrombosis. 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