{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T08:31:30Z","timestamp":1774686690423,"version":"3.50.1"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[1996,5,1]],"date-time":"1996-05-01T00:00:00Z","timestamp":830908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["6534"],"award-info":[{"award-number":["6534"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Two-site immunometric assays for determination of the level of intact parathyroid hormone (PTH) in serum have enabled detailed clinical studies of PTH secretion. Fifty- one patients with primary hyperparathyroidism were studied before surgery and 2 years after operation. PTH levels dropped to low values after operation. A rebound increase in PTH concentration occurred from 10 days to 3 months after surgery. Abnormally raised postoperative PTH concentrations were noted in 31 per cent of the patients, who had lower serum concentrations of ionized calcium (Ca2+) than the rest (P &amp;lt; 0\u00b7003). Before operation these patients had a more pronounced hyperparathyroidism than the others. At 2 years after surgery there was still a positive correlation between PTH concentrations before and after surgery (P &amp;lt; 0\u00b7001). The rebound increase in the level of PTH was a general phenomenon probably caused by low Ca2+ concentrations at the time of remineralization of bone. This phenomenon was transient. The positive correlation between preoperative and postoperative PTH concentrations shows that effects of hyperparathyroidism can remain for a long time after surgical cure.<\/jats:p>","DOI":"10.1002\/bjs.1800830524","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T14:15:33Z","timestamp":1172844933000},"page":"665-669","source":"Crossref","is-referenced-by-count":31,"title":["Transient rise in intact parathyroid hormone concentration after surgery for primary hyperparathyroidism"],"prefix":"10.1093","volume":"83","author":[{"given":"L-E","family":"Tisell","sequence":"first","affiliation":[{"name":"Department of Surgery, Sahlgrenska University Hospital , Goteborg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Jansson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sahlgrenska University Hospital , Goteborg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sahlgrenska University Hospital , Goteborg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Lundberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry, Sahlgrenska University Hospital , Goteborg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Lindstedt","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry, Sahlgrenska University Hospital , Goteborg,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1996,5,1]]},"reference":[{"key":"2024092910101832200_bib1","first-page":"926","article-title":"Studies in patients with hyperparathyroidism using a new two-site immunochemiluminometric assay for circulating intact (1\u201384) parathyroid hormone","volume":"102","author":"Curley","year":"1987","journal-title":"Surgery"},{"key":"2024092910101832200_bib2","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1093\/clinchem\/33.8.1364","article-title":"Highly sensitive two-site immunoradiometric assay of parathyrin, and its clinical utility in evaluating patients with hypercalcemia","volume":"33","author":"Nussbaum","year":"1987","journal-title":"Clin Chem"},{"key":"2024092910101832200_bib3","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1093\/clinchem\/35.2.340","article-title":"Assay of \u2018intact\u2019 parathyrin in the immediate and long-term postoperative follow-up of patients treated for hyperparathyroidism or thyroid tumor","volume":"35","author":"Lundberg","year":"1989","journal-title":"Clin Chem"},{"key":"2024092910101832200_bib4","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/clinchem\/35.6.1019","article-title":"Hypercalcemia in a patient with mammary carcinoma; metastases or primary hyperparathyroidismarticle-title","volume":"35","author":"Nystrom","year":"1989","journal-title":"Clin Chem"},{"key":"2024092910101832200_bib5","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1210\/jcem-66-3-495","article-title":"Recovery of parathyroid hormone secretion after parathyroid adenomectomy","volume":"66","author":"Brasier","year":"1988","journal-title":"J Clin Endocrinol Metab"},{"key":"2024092910101832200_bib6","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/0002-9343(74)90808-0","article-title":"Treatment of primary hyperparathyroidism","volume":"56","author":"Purnell","year":"1974","journal-title":"Am J Med"},{"key":"2024092910101832200_bib7","first-page":"1021","article-title":"Parathyroid hormone: before and after parathyroidectomy","volume":"100","author":"Duh","year":"1986","journal-title":"Surgery"},{"key":"2024092910101832200_bib8","first-page":"898","article-title":"Parathyroid metabolism after operative treatment of hypercalcemic (primary) hyperparathyroidism","volume":"102","author":"Irvin","year":"1987","journal-title":"Surgery"},{"key":"2024092910101832200_bib9","first-page":"549","article-title":"Autotransplantation of diseased parathyroid glands into subcutaneous abdominal adipose tissue","volume":"101","author":"Jansson","year":"1987","journal-title":"Surgery"},{"key":"2024092910101832200_bib10","first-page":"344","article-title":"Eine Methode zur direkten Bestimmung des Creatinins in Serum und Harnohne Enteiweissung nach einer modifizierten Jaff\u00e9 - Methode","volume":"12","author":"Helger","year":"1974","journal-title":"Zeitschrift f\u00fcr Klinische Chemie und Klinische Biochemie"},{"key":"2024092910101832200_bib11","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3109\/00365517409082499","article-title":"Committee on Enzymes of the Scandinavian Society for Clinical Chemistry and Clinical Physiology. 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