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A total of 22 patients were lost to follow-up and five were excluded as maintenance H2 blockers were required. Of the remaining 530 patients at risk, 169 (32 per cent) developed another complication (166 bleeding, three perforations) over a median follow-up period of 36 months. Patients with duodenal ulcers at the time of bleeding, previous history of peptic ulcer, previous bleeding, history of dyspepsia longer than 3 months, and a short interval between previous ulcer complications and the index bleed were more likely to develop further complications. Sex, age, smoking, coexisting illness, non-steroidal anti-inflammatory drugs intake and time taken to achieve ulcer healing had no predictive value.<\/jats:p>","DOI":"10.1002\/bjs.1800830635","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T00:25:41Z","timestamp":1172881541000},"page":"840-844","source":"Crossref","is-referenced-by-count":9,"title":["Risk of further ulcer complications after an episode of peptic ulcer bleeding"],"prefix":"10.1093","volume":"83","author":[{"given":"E K W","family":"Ng","sequence":"first","affiliation":[{"name":"Combined Endoscopy Unit, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S C S","family":"Chung","sequence":"additional","affiliation":[{"name":"Combined Endoscopy Unit, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J T F","family":"Lau","sequence":"additional","affiliation":[{"name":"Centre for Clinical Trials and Epidemiological Research, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J J Y","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J W C","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S A","family":"Raimes","sequence":"additional","affiliation":[{"name":"Combined Endoscopy Unit, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A C W","family":"Chan","sequence":"additional","affiliation":[{"name":"Combined Endoscopy Unit, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A K C","family":"Li","sequence":"additional","affiliation":[{"name":"Combined Endoscopy Unit, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong ,","place":["Hong Kong"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1996,6,1]]},"reference":[{"key":"2024092909423778300_bib1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0889-8553(21)00462-3","article-title":"Bleeding peptic ulcer. 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