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The commonest histological diagnoses were pleomorphic adenoma (n = 776) and adenolymphoma (n = 159). A total of 244 carcinomas were seen (adenoid cystic carcinoma, n = 75). Treatment was primarily surgical, conservative where possible, and determined by tumour extent and not histology. Adjuvant radiation therapy was used in over half the definitively treated malignancies. The recurrence rate following the treatment of 551 new parotid pleomorphic adenomas was 1.6 per cent at median follow-up 12.5 (range 1-34)years, increasing to 15 per cent the secondarily referred group (n = 170). For patients with definitively treated primary salivary carcinomas (n = 148), the disease-free survival rate at 5, 10 and 15 years was 58, 47 and 45 per cent respectively. Using multivariate analysis, clinical stage was the most important predictor of survival; the 10-year survival rate for stages I-IV was 96, 70, 47 and 19 per cent respectively.<\/jats:p>","DOI":"10.1002\/bjs.1800831228","type":"journal-article","created":{"date-parts":[[2007,2,28]],"date-time":"2007-02-28T21:21:13Z","timestamp":1172697673000},"page":"1750-1754","source":"Crossref","is-referenced-by-count":136,"title":["Long-term follow-up of over 1000 patients with salivary gland tumours treated in a single centre"],"prefix":"10.1093","volume":"83","author":[{"given":"A","family":"Renehan","sequence":"first","affiliation":[{"name":"University Depamnent of Surgety, University Hospital of South Manchester and Christie Hospital , Manchester,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E N","family":"Gleave","sequence":"additional","affiliation":[{"name":"University Depamnent of Surgety, University Hospital of South Manchester and Christie Hospital , Manchester,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B D","family":"Hancock","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Wythenshawe Hospital , Manchester,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Smith","sequence":"additional","affiliation":[{"name":"Imperial Cancer Research Fund, Clinical Oncology Unit , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"McGurk","sequence":"additional","affiliation":[{"name":"Salivary Gland Service, Department of Oral and Maxillofacial Surgery, United Medical and Dental Schools, Guy's Hospital , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1996,12,1]]},"reference":[{"key":"2024092909492861600_bib1","volume-title":"Office of Population Censuses and Surveys. 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