{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:01:13Z","timestamp":1777647673019,"version":"3.51.4"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2003,1,7]],"date-time":"2003-01-07T00:00:00Z","timestamp":1041897600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,1,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The incidence and consequences of bacteraemia associated with diathermy and stapled haemorrhoidectomy have not been studied previously.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Two hundred and five healthy patients randomized to stapled haemorrhoidectomy or diathermy haemorrhoidectomy had perioperative blood cultures taken. The clinical sequelae of bacteraemia and complications of surgery were assessed prospectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Six patients were excluded for protocol violations. Eleven (11 per cent) of 101 patients with stapled and five (5 per cent) of 98 who had diathermy haemorrhoidectomy had positive blood cultures for organisms after haemorrhoidectomy, predominantly anaerobes commonly found within the bacterial flora of the anorectum (P = 0\u00b719). Transient postoperative pyrexia in several patients did not correlate with detected bacteraemia and settled spontaneously without treatment. There were no serious complications from either operative technique, and no clinical consequences from proven bacteraemia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Transient bacteraemia may complicate surgical haemorrhoidectomy but has no serious clinical consequences for healthy adults.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.4057","type":"journal-article","created":{"date-parts":[[2003,1,29]],"date-time":"2003-01-29T15:33:23Z","timestamp":1043854403000},"page":"222-226","source":"Crossref","is-referenced-by-count":32,"title":["Prospective randomized study of bacteraemia in diathermyand stapled haemorrhoidectomy"],"prefix":"10.1093","volume":"90","author":[{"given":"A","family":"Maw","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Concepcion","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K W","family":"Eu","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Seow-Choen","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S M","family":"Heah","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C L","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A L","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Singapore General Hospital, Outram Road, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2003,1,7]]},"reference":[{"key":"2021070911305038700_bib1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF02603422","article-title":"Bacteremia after proctoscopy and hemorrhoidal injection sclerotherapy","volume":"24","author":"Adami","year":"1981","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib2","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/BF02590908","article-title":"Bacteremias associated with routine hemorrhoidectomies","volume":"19","author":"Bonardi","year":"1976","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib3","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/0002-8703(60)90117-4","article-title":"Bacteremia following sigmoidoscopy","volume":"60","author":"Buchman","year":"1960","journal-title":"Am Heart J"},{"key":"2021070911305038700_bib4","doi-asserted-by":"crossref","first-page":"715","DOI":"10.2214\/ajr.130.4.715","article-title":"Bacteremia during barium enema study","volume":"130","author":"Butt","year":"1978","journal-title":"AJR Am J Roentgenol"},{"key":"2021070911305038700_bib5","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1136\/gut.18.8.678","article-title":"Colonoscopy and bacteraemia","volume":"18","author":"Coughlin","year":"1977","journal-title":"Gut"},{"key":"2021070911305038700_bib6","first-page":"173","article-title":"Colonoscopy associated bacteremia","volume":"142","author":"Dickman","year":"1976","journal-title":"Surg Gynecol Obstet"},{"key":"2021070911305038700_bib7","doi-asserted-by":"crossref","first-page":"77","DOI":"10.7326\/0003-4819-85-1-77","article-title":"Bacteremia after sigmoidoscopy: another view","volume":"85","author":"Engeling","year":"1976","journal-title":"Ann Intern Med"},{"key":"2021070911305038700_bib8","first-page":"240","article-title":"The absence of bacteremia during colonoscopy","volume":"67","author":"Hartong","year":"1977","journal-title":"Am J Gastroenterol"},{"key":"2021070911305038700_bib9","doi-asserted-by":"crossref","first-page":"658","DOI":"10.7326\/0003-4819-88-5-658","article-title":"Bacteremia after rectal examination","volume":"88","author":"Hoffman","year":"1978","journal-title":"Ann Intern Med"},{"key":"2021070911305038700_bib10","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1001\/archinte.1975.00330060079011","article-title":"Transient bacteremia associated with barium enema","volume":"135","author":"Le Frock","year":"1975","journal-title":"Arch Intern Med"},{"key":"2021070911305038700_bib11","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1056\/NEJM197308302890908","article-title":"Transient bacteremia associated with sigmoidoscopy","volume":"289","author":"Le Frock","year":"1973","journal-title":"N Engl J Med"},{"key":"2021070911305038700_bib12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0016-5107(76)73573-9","article-title":"Does bacteremia follow colonoscopy? II. Results with blood cultures obtained 5, 10, and 15 minutes after colonoscopy","volume":"23","author":"Norfleet","year":"1976","journal-title":"Gastrointest Endosc"},{"key":"2021070911305038700_bib13","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0016-5085(76)80397-6","article-title":"Does bacteremia follow colonoscopy?","volume":"70","author":"Norfleet","year":"1976","journal-title":"Gastroenterology"},{"key":"2021070911305038700_bib14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0016-5107(76)73574-0","article-title":"Bacteremia during colonoscopy","volume":"23","author":"Pelican","year":"1976","journal-title":"Gastrointest Endosc"},{"key":"2021070911305038700_bib15","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1001\/archsurg.1979.01370320069012","article-title":"Is there postdefecation bacteremia?","volume":"114","author":"Slavin","year":"1979","journal-title":"Arch Surg"},{"key":"2021070911305038700_bib16","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3109\/00365527809179831","article-title":"Endoscopy-related bacteremia","volume":"13","author":"Stray","year":"1978","journal-title":"Scand J Gastroenterol"},{"key":"2021070911305038700_bib17","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1056\/NEJM195710172571607","article-title":"Evaluation of blood cultures after sigmoidoscopy","volume":"257","author":"Unterman","year":"1957","journal-title":"N Engl J Med"},{"key":"2021070911305038700_bib18","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1007\/BF02236713","article-title":"Treatment of external anorectal mucosal prolapse with circular stapler: an easy and effective new surgical technique","volume":"42","author":"Altomare","year":"1999","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib19","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/S0140-6736(99)08362-2","article-title":"Stapling procedure for haemorrhoids versus Milligan\u2013Morgan haemorrhoidectomy: randomised controlled trial","volume":"355","author":"Mehigan","year":"2000","journal-title":"Lancet"},{"key":"2021070911305038700_bib20","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/S0140-6736(00)02208-X","article-title":"Life threatening pelvic sepsis after stapled haemorrhoidectomy","volume":"355","author":"Molloy","year":"2000","journal-title":"Lancet"},{"key":"2021070911305038700_bib21","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1016\/S0140-6736(05)72554-X","article-title":"Haemorrhoid surgery revised","volume":"355","author":"Roos","year":"2000","journal-title":"Lancet"},{"key":"2021070911305038700_bib22","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/BF02251970","article-title":"Prospective trial comparing pain and clinical function after conventional scissors excision\/ligation vs. diathermy excision without ligation for symptomatic prolapsed hemorrhoids","volume":"35","author":"Seow-Choen","year":"1992","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib23","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1007\/s10350-004-6193-1","article-title":"Modified Longo's hemorrhoidectomy","volume":"45","author":"Lloyd","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib24","first-page":"2","volume-title":"Cumulative Techniques and Procedures in Clinical Microbiology","author":"Reller","year":"1982"},{"key":"2021070911305038700_bib25","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S0140-6736(00)00086-6","article-title":"Early promise of stapling technique for haemorrhoidectomy","volume":"355","author":"Fazio","year":"2000","journal-title":"Lancet"},{"key":"2021070911305038700_bib26","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/S0140-6736(00)02632-5","article-title":"Persistent pain and faecal urgency after stapled haemorrhoidectomy","volume":"356","author":"Cheetham","year":"2000","journal-title":"Lancet"},{"key":"2021070911305038700_bib27","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1007\/BF02236847","article-title":"Stapled hemorrhoidectomy\u2014cost and effectiveness. Randomized, controlled trial including incontinence scoring, anorectal manometry, and endoanal ultrasound assessments at up to three months","volume":"43","author":"Ho","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib28","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S0140-6736(99)06122-X","article-title":"Circumferential mucosectomy (stapled haemorrhoidectomy) versus conventional haemorrhoidectomy: randomised controlled trial","volume":"355","author":"Rowsell","year":"2000","journal-title":"Lancet"},{"key":"2021070911305038700_bib29","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1007\/BF02050347","article-title":"Bacteriology of the anal wound after open hemorrhoidectomy. Qualitative and quantitative analysis","volume":"34","author":"de Paula","year":"1991","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib30","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1001\/jama.1974.03230240016004","article-title":"Barium enema septicemia","volume":"227","author":"Day","year":"1974","journal-title":"JAMA"},{"key":"2021070911305038700_bib31","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1001\/jama.1973.03230010038008","article-title":"Barium enema septicemia. Occurrence in a patient with septicemia","volume":"226","author":"Richman","year":"1973","journal-title":"JAMA"},{"key":"2021070911305038700_bib32","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0140-6736(97)09003-X","article-title":"Double-blind randomised controlled trial of effect of metronidazole on pain after day-case haemorrhoidectomy","volume":"351","author":"Carapeti","year":"1998","journal-title":"Lancet"},{"key":"2021070911305038700_bib33","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/BF02554261","article-title":"Early recognition and successful management of pelvic cellulitis following hemorrhoidal banding","volume":"29","author":"Clay","year":"1986","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib34","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1001\/archsurg.1988.01400290136024","article-title":"Septic complications of hemorrhoidal banding","volume":"123","author":"Quevedo-Bonilla","year":"1988","journal-title":"Arch Surg"},{"key":"2021070911305038700_bib35","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/BF02554242","article-title":"Retroperitoneal abscess following sclerotherapy for hemorrhoids","volume":"28","author":"Ribbans","year":"1985","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib36","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/BF02560424","article-title":"Hemorrhoidal banding. A warning","volume":"28","author":"Russell","year":"1985","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib37","first-page":"383","article-title":"Pelvic cellulitis: a life-threatening complication of hemorrhoidal banding","volume":"103","author":"Scarpa","year":"1988","journal-title":"Surgery"},{"key":"2021070911305038700_bib38","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF02554339","article-title":"Severe complication of rubber band ligation of internal hemorrhoids","volume":"30","author":"Shemesh","year":"1987","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib39","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF02554954","article-title":"An unusual complication of rubber band ligation of hemorrhoids","volume":"30","author":"Wechter","year":"1987","journal-title":"Dis Colon Rectum"},{"key":"2021070911305038700_bib40","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1007\/s10350-004-6304-z","article-title":"Retroperitoneal sepsis complicating stapled hemorrhoidectomy: report of a case and review of the literature","volume":"45","author":"Maw","year":"2002","journal-title":"Dis Colon Rectum"}],"container-title":["British Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/90\/2\/222\/36726917\/bjs4057.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/90\/2\/222\/36726917\/bjs4057.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T21:00:56Z","timestamp":1625864456000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/90\/2\/222\/6143227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,7]]},"references-count":40,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2003,1,7]]},"published-print":{"date-parts":[[2003,1,28]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.4057","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2003,2]]},"published":{"date-parts":[[2003,1,7]]}}}