{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T01:21:24Z","timestamp":1770340884748,"version":"3.49.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2003,4,7]],"date-time":"2003-04-07T00:00:00Z","timestamp":1049673600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Total gastrectomy with D2 dissection is the standard treatment in Japan for early upper-third gastric cancer. The purpose of this study was to confirm the safety and radicality of proximal gastrectomy as an alternative operation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Between 1993 and 1999, 45 patients with an apparent primary early gastric cancer in the upper third of the stomach were treated by proximal gastrectomy with jejunal interposition. The spleen was preserved, but the suprapancreatic nodes were cleared.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Histology confirmed early gastric cancer in 37 patients while eight had advanced disease. Nodal metastasis was observed in six patients. There was no hospital death and no early postoperative complications. One patient died from nodal recurrence and two from unrelated causes. Two patients had reflux symptoms without endoscopic oesophagitis. Mean weight loss was 11\u00b75 per cent of initial bodyweight.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Proximal gastrectomy for early upper-third gastric cancer can be performed safely with an excellent cure rate. This procedure deserves further clinical evaluation to assess patients' quality of life.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.4106","type":"journal-article","created":{"date-parts":[[2003,7,7]],"date-time":"2003-07-07T10:05:01Z","timestamp":1057572301000},"page":"850-853","source":"Crossref","is-referenced-by-count":117,"title":["Prospective study of proximal gastrectomy for early gastric cancer in the upper third of the stomach"],"prefix":"10.1093","volume":"90","author":[{"given":"H","family":"Katai","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology, National Cancer Centre Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Sano","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, National Cancer Centre Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Fukagawa","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, National Cancer Centre Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Shinohara","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, National Cancer Centre Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Sasako","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, National Cancer Centre Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2003,4,7]]},"reference":[{"key":"2021070911334245800_bib1","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1002\/1097-0142(20001215)89:12<2555::AID-CNCR6>3.0.CO;2-R","article-title":"Early carcinoma of the gastric cardia in Japan: is it different from that in the West?","volume":"89","author":"Okabayashi","year":"2000","journal-title":"Cancer"},{"key":"2021070911334245800_bib2","first-page":"46","volume-title":"Cancer Statistics in Japan 2001","author":"Kakizoe","year":"2001"},{"key":"2021070911334245800_bib3","first-page":"293","volume-title":"Gastric Cancer","author":"Kinoshita","year":"1993"},{"key":"2021070911334245800_bib4","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/PL00011681","article-title":"Japanese Classification of Gastric Carcinoma (2nd English edn)","volume":"1","author":"Japanese Gastric Cancer Association","year":"1998","journal-title":"Gastric Cancer"},{"key":"2021070911334245800_bib5","first-page":"223","volume-title":"Gastric Cancer","author":"Sasako","year":"1997"},{"key":"2021070911334245800_bib6","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1038\/sj.bjc.6690243","article-title":"Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. 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