{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:36:35Z","timestamp":1791264995984,"version":"4.1.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2003,4,30]],"date-time":"2003-04-30T00:00:00Z","timestamp":1051660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,4,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Oral Gastrografin\u00ae has been used to differentiate partial from complete small bowel obstruction (SBO). It may have a therapeutic effect and predict the need for early surgery in adhesive SBO. The aim of this study was to determine whether contrast examination in the management of SBO allows an early oral intake and reduces hospital stay.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Eighty-three patients admitted between February 2000 and November 2001 with 90 episodes of symptoms and signs suggestive of postoperative adhesive SBO were randomized into two groups, a control group and Gastrografin\u00ae group. Patients in the control group were treated conservatively. If symptoms of strangulation developed or the obstruction did not resolve spontaneously after 4\u20135 days, a laparotomy was performed. Patients in the Gastrografin\u00ae group received 100 ml Gastrografin\u00ae. Those in whom the contrast medium reached the colon in 24 h were considered to have partial SBO, and were fed orally. If Gastrografin\u00ae failed to reach the colon and the patient did not improve in the following 24 h a laparotomy was performed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Conservative treatment was successful in 77 episodes (85\u00b76 per cent) and 13 (14\u00b74 per cent) required operation. Among patients treated conservatively, hospital stay was shorter in the Gastrografin\u00ae group (P &amp;lt; 0\u00b7001). All patients in whom contrast medium reached the colon tolerated an early oral diet. Gastrografin\u00ae did not reduce the need for operation (P = 1\u00b7000). No patient died in either group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Oral Gastrografin\u00ae helps in the management of patients with adhesive SBO and allows a shorter hospital stay.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.4150","type":"journal-article","created":{"date-parts":[[2003,5,2]],"date-time":"2003-05-02T10:01:45Z","timestamp":1051869705000},"page":"542-546","source":"Crossref","is-referenced-by-count":128,"title":["Randomized clinical study of Gastrografin\u00ae administration in patients with adhesive small bowel obstruction"],"prefix":"10.1093","volume":"90","author":[{"given":"S","family":"Biondo","sequence":"first","affiliation":[{"name":"Department of Surgery, Hospital Universitario de Bellvitge, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Par\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Universitario de Bellvitge, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Mora","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Universitario de Bellvitge, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Mart\u00ed Ragu\u00e9","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Universitario de Bellvitge, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Kreisler","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Universitario de Bellvitge, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Jaurrieta","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Universitario de Bellvitge, University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2003,4,30]]},"reference":[{"key":"2021070911322121100_bib1","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1002\/bjs.1800741105","article-title":"Current spectrum of intestinal obstruction","volume":"74","author":"McEntee","year":"1987","journal-title":"Br J Surg"},{"key":"2021070911322121100_bib2","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0039-6109(16)44482-8","article-title":"Obstruction of the large and small intestine","volume":"68","author":"Richards","year":"1988","journal-title":"Surg Clin North Am"},{"key":"2021070911322121100_bib3","first-page":"145","article-title":"Partial small bowel obstruction","volume":"95","author":"Brolin","year":"1984","journal-title":"Surgery"},{"key":"2021070911322121100_bib4","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/00000658-200004000-00012","article-title":"Complications and death after surgical treatment of small bowel obstruction: a 35-year institutional experience","volume":"231","author":"Fevang","year":"2000","journal-title":"Ann Surg"},{"key":"2021070911322121100_bib5","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0002-9610(05)80414-3","article-title":"How conservatively can postoperative small bowel obstruction be treated?","volume":"165","author":"Seror","year":"1993","journal-title":"Am J Surg"},{"key":"2021070911322121100_bib6","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/00000658-198708000-00002","article-title":"Use of tubes and radiographs in the management of small bowel obstruction","volume":"206","author":"Brolin","year":"1987","journal-title":"Ann Surg"},{"key":"2021070911322121100_bib7","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1007\/s002689900622","article-title":"Oral urografin in postoperative small bowel obstruction","volume":"23","author":"Chen","year":"1999","journal-title":"World J Surg"},{"key":"2021070911322121100_bib8","first-page":"433","article-title":"Therapeutic effect of oral Gastrografin\u00ae in adhesive, partial small-bowel obstruction: a prospective randomized trial","volume":"115","author":"Assalia","year":"1994","journal-title":"Surgery"},{"key":"2021070911322121100_bib9","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1046\/j.1365-2168.1998.00919.x","article-title":"Water-soluble contrast study predicts the need for early surgery in adhesive small bowel obstruction","volume":"85","author":"Chen","year":"1998","journal-title":"Br J Surg"},{"key":"2021070911322121100_bib10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/110241500750009681","article-title":"Upper gastrointestinal contrast study in the management of small bowel obstruction. 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