{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:35:33Z","timestamp":1767706533211},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2004,3,22]],"date-time":"2004-03-22T00:00:00Z","timestamp":1079913600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,4,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim of this study was to compare the long-term results of laparoscopic and open antireflux surgery in a randomized clinical trial by investigating subjective and objective outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Sixty patients with gastro-oesophageal reflux disease (GORD) were randomized to laparoscopic or open 360 \u00b0 fundoplication. Subjective evaluation using disease-specific and generic questionnaires and structured interviews, and objective evaluation by endoscopy, oesophageal manometry and 24-h pH monitoring, were performed before operation and 1 month, 6 months and 5 years after surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Two patients in the laparoscopic group had reoperations for hiatal stricture; one patient in the open group had repair of an incisional hernia, and one patient in each group had surgery for intestinal obstruction. There were no differences in the subjective outcomes of diet, sleep, medication, patient satisfaction and symptoms of GORD after 5 years. Nor were there any differences in objective outcomes determined by endoscopy, manometry or 24-h pH monitoring. Well-being was decreased in all patients before operation but was restored to normal or above-normal values after fundoplication, regardless of the type of surgery. Seven of 28 patients in the open group had complaints regarding the scar.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Elimination of GORD symptoms improved well-being and eliminated the need for daily acid suppression in most patients, no matter which procedure was employed. These results were apparent 1 month after the operation and were still valid 5 years later.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.4483","type":"journal-article","created":{"date-parts":[[2004,4,12]],"date-time":"2004-04-12T07:00:46Z","timestamp":1081753246000},"page":"552-559","source":"Crossref","is-referenced-by-count":63,"title":["Randomized clinical trial of laparoscopic <i>versus<\/i> open fundoplication for gastro-oesophageal reflux"],"prefix":"10.1093","volume":"91","author":[{"given":"G","family":"Nilsson","sequence":"first","affiliation":[{"name":"Department of Nursing, Lund University, Lund, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Wenner","sequence":"additional","affiliation":[{"name":"Department of Surgery, Lund University, Lund, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Larsson","sequence":"additional","affiliation":[{"name":"Department of Nursing, Lund University, Lund, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Johnsson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Lund University, Lund, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2004,3,22]]},"reference":[{"key":"2021070907145599500_bib1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1365-2168.2002.01990.x","article-title":"Long-term results of antireflux surgery indicate the need for a randomized clinical trial","volume":"89","author":"Sandbu","year":"2002","journal-title":"Br J Surg"},{"key":"2021070907145599500_bib2","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1007\/s00464-001-9043-4","article-title":"Short-term outcome after laparoscopic and open 360 degrees fundoplication. A prospective randomized trial","volume":"15","author":"Wenner","year":"2001","journal-title":"Surg Endosc"},{"key":"2021070907145599500_bib3","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1080\/003655202317315999","article-title":"Randomized clinical trial of laparoscopic versus open fundoplication: evaluation of psychological well-being and changes in everyday life from a patient perspective","volume":"37","author":"Nilsson","year":"2002","journal-title":"Scand J Gastroenterol"},{"key":"2021070907145599500_bib4","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1046\/j.1365-2168.2000.01471.x","article-title":"Randomized clinical trial of laparoscopic versus open fundoplication: blind evaluation of recovery and discharge period","volume":"87","author":"Nilsson","year":"2000","journal-title":"Br J Surg"},{"key":"2021070907145599500_bib5","volume-title":"Nursing Research: Principles and Methods","author":"Polit","year":"1999","edition":"6th"},{"key":"2021070907145599500_bib6","first-page":"170","volume-title":"Assessment of Quality of Life in Clinical Trials of Cardiovascular Therapies","author":"Dupuy","year":"1984"},{"key":"2021070907145599500_bib7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3109\/00365529609095544","article-title":"Relevance of norm values as part of the documentation of quality of life instruments for use in upper gastrointestinal disease","volume":"221","author":"Dimenas","year":"1996","journal-title":"Scand J Gastroenterol Suppl"},{"key":"2021070907145599500_bib8","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3109\/00365529309098272","article-title":"Quality of life in patients with upper gastrointestinal symptoms. An improved evaluation of treatment regimens?","volume":"28","author":"Dimenas","year":"1993","journal-title":"Scand J Gastroenterol"},{"key":"2021070907145599500_bib9","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/BF02310555","article-title":"Coefficient alpha and the internal structures of tests","volume":"16","author":"Cronbach","year":"1951","journal-title":"Psychometrica"},{"key":"2021070907145599500_bib10","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1001\/archsurg.1995.01430090100029","article-title":"Stenosis of the esophageal hiatus following laparoscopic fundoplication","volume":"130","author":"Watson","year":"1995","journal-title":"Arch Surg"},{"key":"2021070907145599500_bib11","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1001\/jama.285.18.2331","article-title":"Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial","volume":"285","author":"Spechler","year":"2001","journal-title":"JAMA"},{"key":"2021070907145599500_bib12","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1001\/archsurg.1995.01430030059011","article-title":"Patient satisfaction following laparoscopic and open antireflux surgery","volume":"130","author":"Rattner","year":"1995","journal-title":"Arch Surg"},{"key":"2021070907145599500_bib13","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.3109\/00365529609036886","article-title":"Quality of life assessment after laparoscopic and open fundoplications. Results of a prospective, clinical study","volume":"31","author":"Blomqvist","year":"1996","journal-title":"Scand J Gastroenterol"},{"key":"2021070907145599500_bib14","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s004649900386","article-title":"Laparoscopic versus conventional Nissen fundoplication. A prospective randomized study","volume":"11","author":"Laine","year":"1997","journal-title":"Surg Endosc"},{"key":"2021070907145599500_bib15","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0140-6736(99)03097-4","article-title":"Laparoscopic or conventional Nissen fundoplication for gastro-oesophageal reflux disease: randomised clinical trial. The Netherlands Antireflux Surgery Study Group","volume":"355","author":"Bais","year":"2000","journal-title":"Lancet"},{"key":"2021070907145599500_bib16","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1007\/s004640000261","article-title":"Comparison of laparoscopic and open Nissen fundoplication 2 years after operation. A prospective randomized trial","volume":"14","author":"Heikkinen","year":"2000","journal-title":"Surg Endosc"},{"key":"2021070907145599500_bib17","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00464-001-9103-9","article-title":"Long-term results of laparoscopic antireflux surgery","volume":"16","author":"Granderath","year":"2002","journal-title":"Surg Endosc"},{"key":"2021070907145599500_bib18","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s00464-002-8912-9","article-title":"Surgical trial investigating nocturnal gastroesophageal reflux and sleep (STINGERS)","volume":"17","author":"Cohen","year":"2003","journal-title":"Surg Endosc"}],"container-title":["British Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.4483","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/91\/5\/552\/36729656\/bjs4483.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/91\/5\/552\/36729656\/bjs4483.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T16:34:04Z","timestamp":1625848444000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/91\/5\/552\/6150972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3,22]]},"references-count":18,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2004,3,22]]},"published-print":{"date-parts":[[2004,4,11]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.4483","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2004,5]]},"published":{"date-parts":[[2004,3,22]]}}}