{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T12:17:38Z","timestamp":1781525858335,"version":"3.54.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2004,3,22]],"date-time":"2004-03-22T00:00:00Z","timestamp":1079913600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,4,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Use of total parenteral nutrition (TPN) in patients with acute intestinal failure due to enteric fistulation might be avoided if a simpler means of nutritional support was available. The aim of this study was to determine whether feeding via an intestinal fistula (fistuloclysis) would obviate the need for TPN.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Fistuloclysis was attempted in 12 patients with jejunocutaneous or ileocutaneous fistulas with mucocutaneous continuity. Feeding was achieved by inserting a gastrostomy feeding tube into the intestine distal to the fistula. Infusion of enteral feed was increased in a stepwise manner, without reinfusion of chyme, until predicted nutritional requirements could be met by a combination of fistuloclysis and regular diet, following which TPN was withdrawn. Energy requirements and nutritional status were assessed before starting fistuloclysis and at the time of reconstructive surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Fistuloclysis replaced TPN entirely in 11 of 12 patients. Nutritional status was maintained for a median of 155 (range 19\u2013422) days until reconstructive surgery could be safely undertaken in nine patients. Two patients who did not undergo surgery remained nutritionally stable over at least 9 months. TPN had to be recommenced in one patient. There were no complications associated with fistuloclysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Fistuloclysis appears to provide effective nutritional support in selected patients with enterocutaneous fistula.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.4520","type":"journal-article","created":{"date-parts":[[2004,4,12]],"date-time":"2004-04-12T07:01:07Z","timestamp":1081753267000},"page":"625-631","source":"Crossref","is-referenced-by-count":112,"title":["Fistuloclysis can successfully replace parenteral feeding in the nutritional support of patients with enterocutaneous fistula"],"prefix":"10.1093","volume":"91","author":[{"given":"A","family":"Teubner","sequence":"first","affiliation":[{"name":"Intestinal Failure Unit, Department of Surgery, Hope Hospital, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Morrison","sequence":"additional","affiliation":[{"name":"Intestinal Failure Unit, Department of Surgery, Hope Hospital, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H R","family":"Ravishankar","sequence":"additional","affiliation":[{"name":"Intestinal Failure Unit, Department of Surgery, Hope Hospital, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I D","family":"Anderson","sequence":"additional","affiliation":[{"name":"Intestinal Failure Unit, Department of Surgery, Hope Hospital, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N A","family":"Scott","sequence":"additional","affiliation":[{"name":"Intestinal Failure Unit, Department of Surgery, Hope Hospital, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G L","family":"Carlson","sequence":"additional","affiliation":[{"name":"Intestinal Failure Unit, Department of Surgery, Hope Hospital, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2004,3,22]]},"reference":[{"key":"2021070907133055000_bib1","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1002\/bjs.1800830434","article-title":"Laparotomy for abdominal sepsis in the critically ill","volume":"83","author":"Anderson","year":"1996","journal-title":"Br J Surg"},{"key":"2021070907133055000_bib2","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/bjs.1800730405","article-title":"\u2018Laparostomy\u2019: a technique for the management of intractable abdominal sepsis","volume":"73","author":"Mughal","year":"1986","journal-title":"Br J Surg"},{"key":"2021070907133055000_bib3","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1080\/110241500750009690","article-title":"Open management of the abdomen and planned reoperations in severe bacterial peritonitis","volume":"166","author":"Bosscha","year":"2000","journal-title":"Eur J Surg"},{"key":"2021070907133055000_bib4","first-page":"51","volume-title":"Intestinal Failure","author":"Hughes","year":"2001"},{"key":"2021070907133055000_bib5","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0140-6736(91)93403-V","article-title":"Spectrum of intestinal failure in a specialised unit","volume":"337","author":"Scott","year":"1991","journal-title":"Lancet"},{"key":"2021070907133055000_bib6","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1002\/bjs.1800811024","article-title":"Reconstructive abdominal operations after laparostomy and multiple repeat laparotomies for severe intra-abdominal infection","volume":"81","author":"Scripcariu","year":"1994","journal-title":"Br J Surg"},{"key":"2021070907133055000_bib7","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/bjs.1800750615","article-title":"Continuous enteral nutrition during the early adaptive stage of the short bowel syndrome","volume":"75","author":"Levy","year":"1988","journal-title":"Br J Surg"},{"key":"2021070907133055000_bib8","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/S0022-3468(99)90575-4","article-title":"Mucous fistula refeeding in neonates with the short bowel syndrome","volume":"34","author":"Al-Harbi","year":"1999","journal-title":"J Pediatr Surg"},{"key":"2021070907133055000_bib9","first-page":"5","article-title":"Predicting basal metabolic rate. 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