{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T10:35:37Z","timestamp":1718706937993},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2004,4,13]],"date-time":"2004-04-13T00:00:00Z","timestamp":1081814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,4,13]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The degree which the various reconstruction techniques prevent bile reflux after gastroduodenal surgery has been poorly studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Bile exposure in the intestinal tract just proximal to the jejunal loop was measured with the Bilitec 2000\u00ae device for 24 h after gastroduodenal surgery in three groups of patients. Group 1 comprised 24 patients with a 60-cm Henley's loop after total gastrectomy. Group 2 included 31 patients with a 60-cm Roux-en-Y loop after total (22 patients) or subtotal (nine) gastrectomy. Group 3 contained 21 patients with a 60-cm Roux-en-Y loop anastomosed to the proximal duodenum as part of a duodenal switch operation for pathological transpyloric duodenogastric reflux. Bile exposure, measured as the percentage time with bile absorbance greater than 0\u00b725, was classified as nil, within the range of a control population of healthy subjects, or pathological (above the 95th percentile for the control population). Reflux symptoms were scored and all patients had upper gastrointestinal endoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Bile was detected in the intestine proximal to the loop in none of 24 patients in group 1, eight of 31 in group 2 and 12 of 21 in group 3 (P &amp;lt; 0\u00b7001). The mean reflux symptom score increased with the degree of bile exposure, and the proportion of patients with oesophagitis or gastritis correlated well with the extent of bile exposure (P &amp;lt; 0\u00b7001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A long Henley's loop was more effective in preventing bile reflux than a long Roux-en-Y loop. Bilitec\u00ae data correlated well with the severity of reflux symptoms and the presence of mucosal lesions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bjs.4569","type":"journal-article","created":{"date-parts":[[2004,4,13]],"date-time":"2004-04-13T13:38:16Z","timestamp":1081863496000},"page":"580-585","source":"Crossref","is-referenced-by-count":9,"title":["Oesophageal and gastric bile exposure after gastroduodenal surgery with Henley's interposition or a Roux-en-Y loop"],"prefix":"10.1093","volume":"91","author":[{"given":"J-Y","family":"Mabrut","sequence":"first","affiliation":[{"name":"Upper Gastrointestinal Surgery Unit, Louvain Medical School, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-M","family":"Collard","sequence":"additional","affiliation":[{"name":"Upper Gastrointestinal Surgery Unit, Louvain Medical School, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Romagnoli","sequence":"additional","affiliation":[{"name":"Upper Gastrointestinal Surgery Unit, Louvain Medical School, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Gutschow","sequence":"additional","affiliation":[{"name":"Upper Gastrointestinal Surgery Unit, Louvain Medical School, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Salizzoni","sequence":"additional","affiliation":[{"name":"Upper Gastrointestinal Surgery Unit, Louvain Medical School, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2004,4,13]]},"reference":[{"key":"2021070907232862900_bib1","first-page":"67","article-title":"De la gastroenterostomie","volume":"1","author":"Roux","year":"1897","journal-title":"Rev Gynecol Chir Abdo"},{"key":"2021070907232862900_bib2","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/bjs.18004016006","article-title":"Gastrectomy with replacement. 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