{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T02:17:44Z","timestamp":1767665864380},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2005,9,26]],"date-time":"2005-09-26T00:00:00Z","timestamp":1127692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,10,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Patients with rectal prolapse have abnormal hindgut motility. This study examined the effect of rectal prolapse surgery on colonic motility.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Twelve patients undergoing sutured rectopexy were studied before and 6 months after surgery by colonic manometry, colonic transit study and clinical assessment of bowel function. The results were compared with those from seven control subjects.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Before surgery colonic pressure was greater in patients than controls (P &amp;lt; 0\u00b7050). Controls responded to a meal stimulus by increasing colonic pressure; this increase was absent in patients. After rectopexy, colonic pressure reduced towards control values and patients' colonic pressure response to a meal returned. High-amplitude propagated contractions (HAPCs) were seen in all controls but in only three patients before and two patients after surgery. Three patients had prolonged colonic transit before and eight after rectopexy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Patients with rectal prolapse have abnormal colonic motility associated with reduced HAPC activity. Rectopexy reduces colonic pressure but fails to restore HAPCs, reduce constipation or improve colonic transit. These observations help explain the pathophysiology of constipation associated with rectal prolapse.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.4990","type":"journal-article","created":{"date-parts":[[2005,9,26]],"date-time":"2005-09-26T13:16:33Z","timestamp":1127740593000},"page":"1417-1422","source":"Crossref","is-referenced-by-count":12,"title":["Prospective study of the effect of rectopexy on colonic motility in patients with rectal prolapse"],"prefix":"10.1093","volume":"92","author":[{"given":"A J","family":"Brown","sequence":"first","affiliation":[{"name":"Department of Coloproctology, Lister Surgical Unit, Glasgow Royal Infirmary, 16 Alexandra Parade, Glasgow G31 2ER, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Nicol","sequence":"additional","affiliation":[{"name":"Department of Coloproctology, Lister Surgical Unit, Glasgow Royal Infirmary, 16 Alexandra Parade, Glasgow G31 2ER, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J H","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Coloproctology, Lister Surgical Unit, Glasgow Royal Infirmary, 16 Alexandra Parade, Glasgow G31 2ER, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R F","family":"McKee","sequence":"additional","affiliation":[{"name":"Department of Coloproctology, Lister Surgical Unit, Glasgow Royal Infirmary, 16 Alexandra Parade, Glasgow G31 2ER, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I G","family":"Finlay","sequence":"additional","affiliation":[{"name":"Department of Coloproctology, Lister Surgical Unit, Glasgow Royal Infirmary, 16 Alexandra Parade, Glasgow G31 2ER, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2005,9,26]]},"reference":[{"key":"2021070906164555000_bib1","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1007\/BF02066977","article-title":"Treatment of complete rectal prolapse: to narrow, to wrap, to suspend, to fix, to encircle, to plicate or to resect?","volume":"16","author":"Kuijpers","year":"1992","journal-title":"World J Surg"},{"key":"2021070906164555000_bib2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/bjs.1800750113","article-title":"Complete rectal prolapse: the anatomical and functional results of treatment by an extended abdominal rectopexy","volume":"75","author":"Mann","year":"1988","journal-title":"Br J Surg"},{"key":"2021070906164555000_bib3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s10350-003-0013-x","article-title":"Strategy for selection of type of operation for rectal prolapse based on clinical criteria","volume":"47","author":"Brown","year":"2004","journal-title":"Dis Colon Rectum"},{"key":"2021070906164555000_bib4","first-page":"145","article-title":"A prospective randomized study of abdominal rectopexy with and without sigmoidectomy in rectal prolapse","volume":"174","author":"McKee","year":"1992","journal-title":"Surg Gynecol Obstet"},{"key":"2021070906164555000_bib5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF00341225","article-title":"Abdominal rectopexy with sigmoidectomy vs. rectopexy alone for rectal prolapse: a prospective, randomized study","volume":"7","author":"Luukkonen","year":"1992","journal-title":"Int J Colorectal Dis"},{"key":"2021070906164555000_bib6","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1002\/bjs.1800781207","article-title":"Lateral ligament division during rectopexy causes constipation but prevents recurrence: results of a prospective randomized study","volume":"78","author":"Speakman","year":"1991","journal-title":"Br J Surg"},{"key":"2021070906164555000_bib7","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1007\/BF02237437","article-title":"Effects of rectal mobilization and lateral ligaments division on colonic and anorectal function","volume":"43","author":"Mollen","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"2021070906164555000_bib8","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/BF02050146","article-title":"Abdominal rectopexy for rectal prolapse. 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