{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:20:09Z","timestamp":1760782809430},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2005,9,26]],"date-time":"2005-09-26T00:00:00Z","timestamp":1127692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,10,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim of this prospective study was to evaluate the role of fluorodeoxyglucose positron emission tomography (FDG-PET) in the staging of high-risk women with primary or recurrent breast cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>FDG-PET was performed in 42 women with a primary breast cancer and unfavourable characteristics, or who had a suspected relapse. FDG-PET and conventional staging methods were compared. In case of abnormality on FDG-PET, confirmation was always attempted.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Increased uptake was found in five of 17 women with a primary cancer. In the 25 women with a suspected relapse, FDG-PET showed increased uptake in 43 areas, 22 correctly confirming the area of suspected relapse and 21 indicating other sites of metastases. Compared with conventional imaging, FDG-PET revealed additional (confirmed) lesions in two women with primary cancers and three with relapse. Patient management was changed for five women.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>FDG-PET is a sensitive diagnostic method for the detection of distant metastatic disease. Its exact role in women with breast cancer remains to be defined.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.5046","type":"journal-article","created":{"date-parts":[[2005,9,26]],"date-time":"2005-09-26T12:19:55Z","timestamp":1127737195000},"page":"1363-1367","source":"Crossref","is-referenced-by-count":24,"title":["Value of fluorodeoxyglucose positron emission tomography in women with breast cancer"],"prefix":"10.1093","volume":"92","author":[{"given":"M L E A","family":"Landheer","sequence":"first","affiliation":[{"name":"Department of Surgery, Rijnstate Hospita, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M G","family":"Steffens","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rijnstate Hospita, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J H G","family":"Klinkenbijl","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rijnstate Hospita, The 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