{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:19:14Z","timestamp":1760782754599},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2005,7,4]],"date-time":"2005-07-04T00:00:00Z","timestamp":1120435200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,10,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Breast-conserving therapy for centrally located tumours has in the past been viewed with reservation, but is now an accepted treatment. There is little published evidence, however, to show that it is safe and cosmetically acceptable.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In a prospective investigation carried out between 1996 and 2002, 44 women had surgery for 45 breast carcinomas with suspected nipple involvement. The breast was conserved and the nipple\u2013areola complex removed. Secondary mastectomy was performed in three women because the tumour was found to reach the resection margin. Forty-one women underwent further observation. The mean tumour size at the time of operation was 18 (range 4\u201350) mm. Six women received preoperative chemotherapy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Histologically, there were seven preinvasive and 35 invasive cancers. No local failure had occurred at a median follow-up of 51 months. Six women developed distant metastasis, of whom five died. The mean score for cosmetic results (evaluated on a scale of 1\u20135 where a score of 1 was excellent) was 1\u00b75 for patients and 1\u00b77 for physicians.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Breast-conserving therapy is a safe and cosmetically acceptable alternative to mastectomy for subareolar breast cancer.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.5083","type":"journal-article","created":{"date-parts":[[2005,7,4]],"date-time":"2005-07-04T15:38:28Z","timestamp":1120491508000},"page":"1368-1371","source":"Crossref","is-referenced-by-count":12,"title":["Breast-conserving surgery with resection of the nipple\u2013areola complex for subareolar breast carcinoma"],"prefix":"10.1093","volume":"92","author":[{"given":"C","family":"Tausch","sequence":"first","affiliation":[{"name":"Department of Surgery, Sisters of Mercy Hospital, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Hintringer","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Sisters of Mercy Hospital, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Kugler","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sisters of Mercy Hospital, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Schmidhammer","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sisters of Mercy Hospital, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Sisters of Mercy Hospital, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Aufschnaiter","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sisters of Mercy Hospital, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2005,7,4]]},"reference":[{"key":"2021070906163493400_bib1","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1002\/1097-0142(19811015)48:8<1863::AID-CNCR2820480825>3.0.CO;2-U","article-title":"Findings from NSABP Protocol No. B-04: comparison of radical mastectomy with alternative treatments. 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