{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T17:31:12Z","timestamp":1762623072786},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2007,5,14]],"date-time":"2007-05-14T00:00:00Z","timestamp":1179100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,8,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The role of surgery in the management of patients with diffuse oesophageal spasm (DOS) remains controversial. The aim of this study was to assess functional results after extended myotomy for DOS.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This prospective study evaluated 20 patients who had extended myotomy (14 cm on the oesophagus and 2 cm below the oesophagogastric junction) with anterior fundoplication via a laparotomy for severe DOS. Median follow-up was 50 (range 6\u201384) months. Functional data were assessed by means of dysphagia (range 0\u20133), chest pain (range 0\u20133) and overall clinical (range 0\u201312, including dysphagia, chest pain, regurgitation, gastro-oesophageal reflux) scores.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>All patients had severe DOS. The median preoperative overall clinical score was 6 (range 3\u20138) with a dysphagia score of at least 2. Median postoperative functional scores were significantly lower than preoperative values (overall clinical score 1 versus 6, dysphagia score 0 versus 3, chest pain score 0 versus 2). At final follow-up, good or excellent results were obtained for overall clinical score in 16 patients, for dysphagia score in 18 and for chest pain score in all 20 patients. Postoperative gastro-oesophageal reflux was noted in two of the 20 patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Extended myotomy with anterior fundoplication is an effective treatment for severe DOS. Medium-term postoperative functional results were excellent, especially in terms of dysphagia and chest pain.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.5761","type":"journal-article","created":{"date-parts":[[2007,5,14]],"date-time":"2007-05-14T11:53:47Z","timestamp":1179143627000},"page":"1113-1118","source":"Crossref","is-referenced-by-count":67,"title":["Functional results after extended myotomy for diffuse oesophageal spasm"],"prefix":"10.1093","volume":"94","author":[{"given":"M","family":"Leconte","sequence":"first","affiliation":[{"name":"Department of Digestive and Endocrine Surgery, Cochin University Hospital (AP-HP), Ren\u00e9 Descartes Paris 5 University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Douard","sequence":"additional","affiliation":[{"name":"Department of Digestive and General Surgery, Georges Pompidou European University Hospital (AP-HP), Ren\u00e9 Descartes Paris 5 University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Gaudric","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Cochin University Hospital (AP-HP), Ren\u00e9 Descartes Paris 5 University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Dumontier","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Cochin University Hospital (AP-HP), Ren\u00e9 Descartes Paris 5 University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Chaussade","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Cochin University Hospital (AP-HP), Ren\u00e9 Descartes Paris 5 University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Dousset","sequence":"additional","affiliation":[{"name":"Department of Digestive and Endocrine Surgery, Cochin University Hospital (AP-HP), Ren\u00e9 Descartes Paris 5 University, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2007,5,14]]},"reference":[{"key":"2021070907295894500_bib1","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/S0140-6736(01)05973-6","article-title":"Oesophageal motility disorders","volume":"358","author":"Richter","year":"2001","journal-title":"Lancet"},{"key":"2021070907295894500_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0003-4975(10)62490-3","article-title":"Surgery for esophageal motor disorders","volume":"34","author":"DeMeester","year":"1982","journal-title":"Ann Thorac Surg"},{"key":"2021070907295894500_bib3","doi-asserted-by":"crossref","first-page":"242","DOI":"10.7326\/0003-4819-100-2-242","article-title":"Diffuse esophageal spasm: a reappraisal","volume":"100","author":"Richter","year":"1984","journal-title":"Ann Intern Med"},{"key":"2021070907295894500_bib4","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0022-5223(19)34663-X","article-title":"Physiologic assessment and surgical management of diffuse esophageal spasm","volume":"104","author":"Eypasch","year":"1992","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2021070907295894500_bib5","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF01308186","article-title":"Manometric patterns using esophageal body and lower sphincter characteristics. 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