{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T16:41:28Z","timestamp":1785688888182,"version":"3.56.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2007,10,10]],"date-time":"2007-10-10T00:00:00Z","timestamp":1191974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,11,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O-POSSUM).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for adenocarcinoma or squamous cell carcinoma of the oesophagus were analysed. The in-hospital mortality predicted by O-POSSUM was compared with the actual value by linear analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Twenty-four (3\u00b76 per cent) of 663 patients died in hospital. The observed : predicted ratio for in-hospital mortality was 0\u00b729. The model had a poor fit (P &amp;lt; 0\u00b7001). The area under the receiver\u2013operator characteristic curve was 0\u00b760 (95 per cent confidence interval 0\u00b747 to 0\u00b772); P = 0\u00b7113). O-POSSUM score was not related to the severity of complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>O-POSSUM overpredicted in-hospital mortality threefold and could not identify patients at higher risk of death. O-POSSUM needs substantial modification before it can be used for comparison of treatment outcomes between centres.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.5850","type":"journal-article","created":{"date-parts":[[2007,10,10]],"date-time":"2007-10-10T13:46:27Z","timestamp":1192023987000},"page":"1521-1526","source":"Crossref","is-referenced-by-count":48,"title":["Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer"],"prefix":"10.1093","volume":"94","author":[{"given":"S M","family":"Lagarde","sequence":"first","affiliation":[{"name":"Department of Surgery, Academic Medical Centre at the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A K D","family":"Maris","sequence":"additional","affiliation":[{"name":"Department of Surgery, Academic Medical Centre at the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S M M","family":"de Castro","sequence":"additional","affiliation":[{"name":"Department of Surgery, Academic Medical Centre at the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O R C","family":"Busch","sequence":"additional","affiliation":[{"name":"Department of Surgery, Academic Medical Centre at the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Obertop","sequence":"additional","affiliation":[{"name":"Department of Surgery, Academic Medical Centre at the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J J B","family":"van Lanschot","sequence":"additional","affiliation":[{"name":"Department of Surgery, Academic Medical Centre at the University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2007,10,10]]},"reference":[{"key":"2021070907401946500_bib1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/01.sla.0000201800.45264.51","article-title":"Operative mortality and procedure volume as predictors of subsequent hospital performance","volume":"243","author":"Birkmeyer","year":"2006","journal-title":"Ann Surg"},{"key":"2021070907401946500_bib2","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.thorsurg.2006.01.008","article-title":"The volume\u2013performance relationship in esophagectomy","volume":"16","author":"Chang","year":"2006","journal-title":"Thorac Surg Clin"},{"key":"2021070907401946500_bib3","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1002\/1097-0142(20010415)91:8<1574::AID-CNCR1168>3.0.CO;2-2","article-title":"Hospital volume and hospital mortality for esophagectomy","volume":"91","author":"van Lanschot","year":"2001","journal-title":"Cancer"},{"key":"2021070907401946500_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1001\/archsurg.137.1.15","article-title":"The POSSUM system of surgical audit","volume":"137","author":"Copeland","year":"2002","journal-title":"Arch Surg"},{"key":"2021070907401946500_bib5","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/bjs.1800780327","article-title":"POSSUM: a scoring system for surgical audit","volume":"78","author":"Copeland","year":"1991","journal-title":"Br J Surg"},{"key":"2021070907401946500_bib6","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/bjs.4414","article-title":"Risk-adjusted prediction of operative mortality in oesophagogastric surgery with O-POSSUM","volume":"91","author":"Tekkis","year":"2004","journal-title":"Br J Surg"},{"key":"2021070907401946500_bib7","volume-title":"TNM Classification of Malignant Tumours","author":"Sobin","year":"2002","edition":"6th"},{"key":"2021070907401946500_bib8","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surg"},{"key":"2021070907401946500_bib9","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/bjs.1800830628","article-title":"An evaluation of the POSSUM surgical scoring system","volume":"83","author":"Whiteley","year":"1996","journal-title":"Br J Surg"},{"key":"2021070907401946500_bib10","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1007\/s10350-004-0704-y","article-title":"Assessment of operative risk in colorectal cancer surgery: the Cleveland Clinic Foundation colorectal cancer model","volume":"47","author":"Fazio","year":"2004","journal-title":"Dis Colon Rectum"},{"key":"2021070907401946500_bib11","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1055\/s-2007-1010211","article-title":"Evaluation of the POSSUM scoring system in lung surgery. Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity","volume":"46","author":"Brunelli","year":"1998","journal-title":"Thorac Cardiovasc Surg"},{"key":"2021070907401946500_bib12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0003-4975(98)00822-4","article-title":"POSSUM scoring system as an instrument of audit in lung resection surgery. Physiological and operative severity score for the enumeration of mortality and morbidity","volume":"67","author":"Brunelli","year":"1999","journal-title":"Ann Thorac Surg"},{"key":"2021070907401946500_bib13","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1053\/ejvs.2001.1557","article-title":"POSSUM and P-POSSUM overpredict mortality for carotid endarterectomy","volume":"23","author":"Kuhan","year":"2002","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"2021070907401946500_bib14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S1015-9584(09)60374-2","article-title":"Comparative audit of abdominal aortic aneurysm repairs using POSSUM scores","volume":"26","author":"Yii","year":"2003","journal-title":"Asian J Surg"},{"key":"2021070907401946500_bib15","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1002\/bjs.4224","article-title":"Evaluation of POSSUM and P-POSSUM scoring systems in assessing outcome after laparoscopic colectomy","volume":"90","author":"Senagore","year":"2003","journal-title":"Br J Surg"},{"key":"2021070907401946500_bib16","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1007\/s10350-005-0290-7","article-title":"A comparison of POSSUM, P-POSSUM and colorectal POSSUM for the prediction of postoperative mortality in patients undergoing colorectal resection","volume":"49","author":"Ramkumar","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"2021070907401946500_bib17","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.1002\/cncr.21888","article-title":"Volume and process of care in high-risk cancer surgery","volume":"106","author":"Birkmeyer","year":"2006","journal-title":"Cancer"},{"key":"2021070907401946500_bib18","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jamcollsurg.2005.12.022","article-title":"Modern 5-year survival of resectable esophageal adenocarcinoma: single institution experience with 263 patients","volume":"202","author":"Portale","year":"2006","journal-title":"J Am Coll Surg"},{"key":"2021070907401946500_bib19","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1245\/ASO.2006.04.040","article-title":"The influence of technical complications on postoperative outcome and survival after esophagectomy","volume":"13","author":"Ferri","year":"2006","journal-title":"Ann Surg Oncol"},{"key":"2021070907401946500_bib20","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.athoracsur.2004.02.068","article-title":"Factors affecting postoperative course and survival after en bloc resection for esophageal carcinoma","volume":"78","author":"Mariette","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"2021070907401946500_bib21","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1097\/01.sla.0000145925.70409.d7","article-title":"Three-field lymphadenectomy for carcinoma of the esophagus and gastroesophageal junction in 174 R0 resections: impact on staging, disease-free survival, and outcome: a plea for adaptation of TNM classification in upper-half esophageal carcinoma","volume":"240","author":"Lerut","year":"2004","journal-title":"Ann Surg"},{"key":"2021070907401946500_bib22","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/00000658-200103000-00006","article-title":"Analysis of reduced death and complication rates after esophageal resection","volume":"233","author":"Whooley","year":"2001","journal-title":"Ann Surg"}],"container-title":["British Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.5850","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/94\/12\/1521\/36686322\/bjs5850.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/94\/12\/1521\/36686322\/bjs5850.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T18:42:13Z","timestamp":1625856133000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/94\/12\/1521\/6156239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10,10]]},"references-count":22,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2007,10,10]]},"published-print":{"date-parts":[[2007,11,16]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.5850","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2007,12]]},"published":{"date-parts":[[2007,10,10]]}}}