{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T01:08:42Z","timestamp":1789002522864,"version":"build-2803163510"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2007,8,30]],"date-time":"2007-08-30T00:00:00Z","timestamp":1188432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,9,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Holmium laser enucleation (HoLEP) is an alternative to transurethral resection (TURP) of the prostate for symptomatic prostatic obstruction.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Randomized controlled trials comparing HoLEP and TURP were identified systematically using Medline, Embase and The Cochrane Library. Primary outcomes were peak urinary flow rate (Qmax), postvoid residual volume, symptom score and quality of life. Secondary outcomes were duration of operation, hospital stay, blood loss, catheterization time and adverse events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There was no statistically significant difference between HoLEP and TURP in terms of Qmax at 6 and 12 months' follow-up. HoLEP was associated with significantly less blood loss, a shorter catheterization time and a shorter hospital stay. TURP was associated with reduced operating time. The techniques were similar in terms of urethral stricture, stress incontinence, transfusion requirement and rate of reintervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>HoLEP and TURP provide a similar improvement in Qmax. HoLEP, however, has several advantages over TURP, despite requiring more operating time. It is at least as safe as TURP in terms of adverse events.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.5916","type":"journal-article","created":{"date-parts":[[2007,8,30]],"date-time":"2007-08-30T10:46:34Z","timestamp":1188470794000},"page":"1201-1208","source":"Crossref","is-referenced-by-count":146,"title":["Meta-analysis of holmium laser enucleation <i>versus<\/i> transurethral resection of the prostate for symptomatic prostatic obstruction"],"prefix":"10.1093","volume":"94","author":[{"given":"A","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Urology, First Affiliated Hospital, Guangxi Medical University, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Urology, First Affiliated Hospital, Guangxi Medical University, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Urology, First Affiliated Hospital, Guangxi Medical University, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Anal and Colorectal Surgery, First Affiliated Hospital, Guangxi Medical University, Guangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2007,8,30]]},"reference":[{"key":"2021070907391131000_bib1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/S0022-5347(17)40732-4","article-title":"Transurethral prostatectomy: practice aspects of the dominant operation in American urology","volume":"141","author":"Holtgrewe","year":"1989","journal-title":"J Urol"},{"key":"2021070907391131000_bib2","first-page":"39","article-title":"There is significant sexual dysfunction following TURP","volume":"77","author":"Dunsmuir","year":"1996","journal-title":"Br J Urol"},{"key":"2021070907391131000_bib3","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0022-5347(17)40731-2","article-title":"Transurethral prostatectomy: immediate and postoperative complications. Cooperative study of 13 participating institutions evaluating 3885 patients","volume":"141","author":"Mebust","year":"1989","journal-title":"J Urol"},{"key":"2021070907391131000_bib4","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1056\/NEJM198904273201705","article-title":"Mortality and reoperation after open and transurethral resection of the prostate for benign prostatic hyperplasia","volume":"320","author":"Roos","year":"1989","journal-title":"N Engl J Med"},{"key":"2021070907391131000_bib5","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1445-2197.1998.tb04697.x","article-title":"Adverse events after prostatectomy in Victorian public hospitals","volume":"68","author":"Ansari","year":"1998","journal-title":"Aust N Z J Surg"},{"key":"2021070907391131000_bib6","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0022-5347(17)59817-1","article-title":"Transurethral prostatectomy: computerized analysis of 2223 consecutive cases","volume":"112","author":"Melchior","year":"1974","journal-title":"J Urol"},{"key":"2021070907391131000_bib7","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0022-5347(17)64980-2","article-title":"Factors influencing the mortality and morbidity of transurethral prostatectomy: a study of 2015 cases","volume":"87","author":"Holtgrewe","year":"1962","journal-title":"J Urol"},{"key":"2021070907391131000_bib8","first-page":"217","article-title":"Laser prostatectomy with the holmium : YAG laser","volume":"1","author":"Chun","year":"1995","journal-title":"Tech Urol"},{"key":"2021070907391131000_bib9","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1089\/end.1995.9.151","article-title":"Combination holmium and Nd : YAG laser ablation of the prostate: initial clinical experience","volume":"9","author":"Gilling","year":"1995","journal-title":"J Endourol"},{"key":"2021070907391131000_bib10","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1111\/j.1464-410X.1992.tb15631.x","article-title":"Laser ablation of the prostate in patients with benign prostatic hypertrophy","volume":"69","author":"Costello","year":"1992","journal-title":"Br J Urol"},{"key":"2021070907391131000_bib11","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1089\/end.1999.13.127","article-title":"Randomized comparison of transurethral electroresection and holmium : YAG laser vaporization for symptomatic benign prostatic hyperplasia","volume":"13","author":"Mottet","year":"1999","journal-title":"J Endourol"},{"key":"2021070907391131000_bib12","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1089\/end.1996.10.459","article-title":"The use of the holmium laser in the treatment of benign prostatic hyperplasia","volume":"10","author":"Gilling","year":"1996","journal-title":"J Endourol"},{"key":"2021070907391131000_bib13","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0090-4295(99)80381-1","article-title":"Holmium laser resection of the prostate: preliminary results of a new method for the treatment of benign prostatic hyperplasia","volume":"47","author":"Gilling","year":"1996","journal-title":"Urology"},{"key":"2021070907391131000_bib14","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1089\/end.1998.12.457","article-title":"Holmium laser enucleation of the prostate (HoLEP) combined with transurethral tissue morcellation: an update on the early clinical experience","volume":"12","author":"Gilling","year":"1998","journal-title":"J Endourol"},{"key":"2021070907391131000_bib15","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1089\/end.2000.14.219","article-title":"Holmium laser enucleation of the prostate with tissue morcellation: initial United States experience","volume":"14","author":"Moody","year":"2000","journal-title":"J Endourol"},{"key":"2021070907391131000_bib16","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1016\/S0022-5347(05)68186-4","article-title":"Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year follow-up","volume":"162","author":"Gilling","year":"1999","journal-title":"J Urol"},{"key":"2021070907391131000_bib17","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0022-5347(05)67914-1","article-title":"Transurethral holmium laser resection of the prostate","volume":"163","author":"Matsuoka","year":"2000","journal-title":"J Urol"},{"key":"2021070907391131000_bib18","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1089\/end.2000.14.533","article-title":"Results of holmium laser resection of the prostate for benign prostatic hyperplasia","volume":"14","author":"Chilton","year":"2000","journal-title":"J Endourol"},{"key":"2021070907391131000_bib19","volume-title":"Methods for Meta-analysis in Medical Research","author":"Sutton","year":"2000"},{"key":"2021070907391131000_bib20","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2307\/3001666","article-title":"The combination of estimates from different experiments","volume":"10","author":"Cochran","year":"1954","journal-title":"Biometrics"},{"key":"2021070907391131000_bib21","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0033-0620(85)80003-7","article-title":"Beta blockade during and after myocardial infarction: an overview of the randomized trials","volume":"27","author":"Yusuf","year":"1985","journal-title":"Prog Cardiovasc Dis"},{"key":"2021070907391131000_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/9780470693926","volume-title":"Systematic Reviews in Health Care: Meta-analysis in Context","author":"Egger","year":"2001","edition":"2nd"},{"key":"2021070907391131000_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Control Clin Trials"},{"key":"2021070907391131000_bib24","doi-asserted-by":"crossref","first-page":"982","DOI":"10.7326\/0003-4819-135-11-200112040-00010","article-title":"Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses","volume":"135","author":"Kjaergard","year":"2001","journal-title":"Ann Intern Med"},{"key":"2021070907391131000_bib25","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0140-6736(98)01085-X","article-title":"Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?","volume":"352","author":"Moher","year":"1998","journal-title":"Lancet"},{"key":"2021070907391131000_bib26","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1016\/S0022-5347(05)00983-3","article-title":"Impact on sexual function of holmium laser enucleation versus transurethral resection of the prostate: results of a prospective, 2-center, randomized trial","volume":"175","author":"Briganti","year":"2006","journal-title":"J Urol"},{"key":"2021070907391131000_bib27","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.urology.2005.12.036","article-title":"Urodynamics after TURP and HoLEP in urodynamically obstructed patients: are there any differences at 1 year of follow-up?","volume":"67","author":"Rigatti","year":"2006","journal-title":"Urology"},{"key":"2021070907391131000_bib28","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.eururo.2006.04.002","article-title":"A randomised trial comparing holmium laser enucleation versus transurethral resection in the treatment of prostates larger than 40 grams: results at 2 years","volume":"50","author":"Wilson","year":"2006","journal-title":"Eur Urol"},{"key":"2021070907391131000_bib29","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1464-410X.2006.05862.x","article-title":"Comparison of standard transurethral resection, transurethral vapor resection and holmium laser enucleation of the prostate for managing benign prostatic hyperplasia of &gt; 40 g","volume":"97","author":"Gupta","year":"2006","journal-title":"BJU Int"},{"key":"2021070907391131000_bib30","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1097\/01.ju.0000136218.11998.9e","article-title":"Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resection of the prostate: a randomized prospective trial in 200 patients","volume":"172","author":"Kuntz","year":"2004","journal-title":"J Urol"},{"key":"2021070907391131000_bib31","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1097\/01.ju.0000140501.68841.a1","article-title":"Holmium laser enucleation versus transurethral resection of the prostate: results from a 2-center, prospective, randomized trial in patients with obstructive benign prostatic hyperplasia","volume":"172","author":"Montorsi","year":"2004","journal-title":"J Urol"},{"key":"2021070907391131000_bib32","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1097\/01.ju.0000086948.55973.00","article-title":"A randomized trial comparing holmium laser enucleation of the prostate with transurethral resection of the prostate for the treatment of bladder outlet obstruction secondary to benign prostatic hyperplasia in large glands (40 to 200 grams)","volume":"170","author":"Tan","year":"2003","journal-title":"J Urol"},{"key":"2021070907391131000_bib33","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0022-5347(05)64070-0","article-title":"Laser prostatectomy versus transurethral resection for treating benign prostatic obstruction: a systematic review","volume":"169","author":"Hoffman","year":"2003","journal-title":"J Urol"},{"key":"2021070907391131000_bib34","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1464-410X.2004.04598.x","article-title":"The development of laser prostatectomy","volume":"93","author":"Te","year":"2004","journal-title":"BJU Int"},{"key":"2021070907391131000_bib35","volume-title":"Undertaking Systematic Reviews of Research on Effectiveness: CRD's Guidance for Carrying Out or Commissioning Reviews","author":"Khan","year":"2001","edition":"2nd"},{"key":"2021070907391131000_bib36","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1097\/01.ju.0000113494.03668.6d","article-title":"A systematic review of holmium laser prostatectomy for benign prostatic hyperplasia","volume":"171","author":"Tooher","year":"2004","journal-title":"J Urol"},{"key":"2021070907391131000_bib37","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/S0022-5347(05)64475-8","article-title":"Transurethral holmium laser enucleation versus transvesical open enucleation for prostate adenoma greater than 100 gm: a randomized prospective trial of 120 patients","volume":"168","author":"Kuntz","year":"2002","journal-title":"J Urol"},{"key":"2021070907391131000_bib38","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1089\/end.2000.14.529","article-title":"Holmium laser enucleation of the prostate for glands larger than 100 g: an endourologic alternative to open prostatectomy","volume":"14","author":"Gilling","year":"2000","journal-title":"J Endourol"},{"key":"2021070907391131000_bib39","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1046\/j.1464-410X.2002.03071.x","article-title":"Holmium laser enucleation of the prostate can be taught: the first learning experience","volume":"90","author":"El-Hakim","year":"2002","journal-title":"BJU Int"},{"key":"2021070907391131000_bib40","first-page":"368","article-title":"Transurethral prostate resection: immediate and postoperative complications. A cooperative study of three participating institutions in three different countries","volume":"165","author":"Poulakis","year":"2001","journal-title":"J Urol"}],"container-title":["British Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.5916","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/94\/10\/1201\/36686432\/bjs5916.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/94\/10\/1201\/36686432\/bjs5916.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T18:41:09Z","timestamp":1625856069000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/94\/10\/1201\/6156216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,30]]},"references-count":40,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2007,8,30]]},"published-print":{"date-parts":[[2007,9,14]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.5916","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2007,10]]},"published":{"date-parts":[[2007,8,30]]}}}