{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:38:05Z","timestamp":1781311085949,"version":"3.54.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Laparoscopic fundoplication is an accepted treatment for symptomatic gastro-oesophageal reflux disease. The aim of this study was to clarify whether total (Nissen) or partial (Toupet) fundoplication is preferable, and whether preoperative oesophageal manometry should be used to determine the degree of fundoplication performed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Preoperative oesophageal manometry was used to stratify 127 patients with established gastro-oesophageal reflux disease into effective (75) and ineffective (52) oesophageal motility groups. Patients in each group were randomized to Nissen (64) or Toupet (63) fundoplication.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>No significant differences between the operative groups were seen in heartburn, regurgitation or other reflux-related symptoms up to 1 year after surgery. Dysphagia of any degree (27 versus 9 per cent; P = 0\u00b7018) and chest pain on eating (22 versus 5 per cent; P = 0\u00b7018) were more prevalent at 1 year in the Nissen group. There were no differences in postoperative symptoms between the effective and ineffective motility groups. Surgery failed in eight patients on postoperative pH criteria, three in the Nissen group and five in the Toupet group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Any differences in the symptomatic outcome of laparoscopic Nissen and Toupet fundoplication appear minimal. There is no reason to tailor the degree of fundoplication to preoperative oesophageal manometry.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.6047","type":"journal-article","created":{"date-parts":[[2007,12,12]],"date-time":"2007-12-12T17:18:06Z","timestamp":1197479886000},"page":"57-63","source":"Crossref","is-referenced-by-count":153,"title":["Randomized clinical trial of laparoscopic total (Nissen) <i>versus<\/i> posterior partial (Toupet) fundoplication for gastro-oesophageal reflux disease based on preoperative oesophageal manometry"],"prefix":"10.1093","volume":"95","author":[{"given":"M I","family":"Booth","sequence":"first","affiliation":[{"name":"Department of Surgery, Royal Berkshire Hospital , Reading,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Stratford","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Physiology, Royal Berkshire Hospital , Reading,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Physiology, Royal Berkshire Hospital , Reading,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T C B","family":"Dehn","sequence":"additional","affiliation":[{"name":"Department of Surgery, Royal Berkshire Hospital , Reading,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,1,1]]},"reference":[{"key":"2024093006362992300_bib1","first-page":"1","article-title":"Post Nissen syndrome","volume":"167","author":"Low","year":"1988","journal-title":"Surg Gynecol Obstet"},{"key":"2024093006362992300_bib2","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1002\/bjs.1800780918","article-title":"A more physiological alternative to total fundoplication for the surgical correction of resistant gastro-esophageal reflux","volume":"78","author":"Watson","year":"1991","journal-title":"Br J Surg"},{"key":"2024093006362992300_bib3","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0022-5223(05)80019-4","article-title":"A tailored approach to antireflux surgery","volume":"110","author":"Kauer","year":"1995","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024093006362992300_bib4","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0002-9610(99)80027-0","article-title":"Minimally invasive surgery for gastroesophageal reflux disease","volume":"170","author":"Patti","year":"1995","journal-title":"Am J Surg"},{"key":"2024093006362992300_bib5","first-page":"35","article-title":"The preoperative evaluation of patients considered for laparoscopic antireflux surgery","volume":"90","author":"Waring","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"2024093006362992300_bib6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1046\/j.1365-2168.1999.00969.x","article-title":"Prospective randomized double-blind trial between laparoscopic Nissen fundoplication and anterior partial fundoplication","volume":"86","author":"Watson","year":"1999","journal-title":"Br J Surg"},{"key":"2024093006362992300_bib7","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1097\/00000658-199706000-00002","article-title":"A randomized, prospective comparison of the Nissen fundoplication versus the Toupet fundoplication for gastroesophageal reflux disease","volume":"225","author":"Laws","year":"1997","journal-title":"Ann Surg"},{"key":"2024093006362992300_bib8","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1053\/gast.2001.25486","article-title":"Esophageal motility in reflux disease before and after fundoplication: a prospective, randomized, clinical, and manometric study","volume":"121","author":"Fibbe","year":"2001","journal-title":"Gastroenterology"},{"key":"2024093006362992300_bib9","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1002\/bjs.4803","article-title":"Randomized double-blind trial of laparoscopic Nissen fundoplication versus anterior partial fundoplication","volume":"92","author":"Baigrie","year":"2005","journal-title":"Br J Surg"},{"key":"2024093006362992300_bib10","first-page":"119","volume-title":"The Esophagus: Handbook and Atlas of Endosocopy","author":"Savary","year":"1978"},{"key":"2024093006362992300_bib11","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/00000658-197610000-00009","article-title":"Patterns of gastroesophageal reflux in health and disease","volume":"184","author":"DeMeester","year":"1976","journal-title":"Ann Surg"},{"key":"2024093006362992300_bib12","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1023\/A:1018802908358","article-title":"Ineffective esophageal motility (IEM): the primary finding in patients with nonspecific esophageal motility disorder","volume":"42","author":"Leite","year":"1997","journal-title":"Dig Dis Sci"},{"key":"2024093006362992300_bib13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/bjs.1800770115","article-title":"Oesophageal manometry and pH recording does not predict the bad results of Nissen fundoplication","volume":"77","author":"Mughal","year":"1990","journal-title":"Br J Surg"},{"key":"2024093006362992300_bib14","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/bjs.1800740533","article-title":"Clinical implications of abnormal oesophageal motility","volume":"74","author":"Bancewicz","year":"1987","journal-title":"Br J Surg"},{"key":"2024093006362992300_bib15","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1007\/PL00012356","article-title":"Tailoring antireflux surgery. A randomized clinical trial","volume":"6","author":"Rydberg","year":"1999","journal-title":"World J Surg"},{"key":"2024093006362992300_bib16","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1046\/j.1442-2050.2002.00229.x","article-title":"Preoperative esophageal body motility does not influence the outcome of laparoscopic Nissen fundoplication for gastroesophageal reflux disease","volume":"15","author":"Booth","year":"2002","journal-title":"Dis Esophagus"},{"key":"2024093006362992300_bib17","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1046\/j.1365-2168.1998.00832.x","article-title":"Oesophageal dysmotility is not associated with poor outcome after laparoscopic Nissen fundoplication","volume":"85","author":"Beckingham","year":"1998","journal-title":"Br J Surg"},{"key":"2024093006362992300_bib18","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s00464-005-0256-9","article-title":"Effects of laparoscopic Nissen fundoplication on esophageal motility: long-term results","volume":"20","author":"Biertho","year":"2006","journal-title":"Surg Endosc"},{"key":"2024093006362992300_bib19","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S1091-255X(99)80079-1","article-title":"Laparoscopic Toupet fundoplication is an inadequate procedure for patients with severe reflux disease","volume":"3","author":"Horvath","year":"1999","journal-title":"J Gastrointest Surg"},{"key":"2024093006362992300_bib20","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1177\/000313480006600302","article-title":"Heartburn is more likely to recur after Toupet fundoplication than Nissen fundoplication","volume":"66","author":"Farrell","year":"2000","journal-title":"Am Surg"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.6047","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/95\/1\/57\/59442204\/bjs6047.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/95\/1\/57\/59442204\/bjs6047.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T06:39:18Z","timestamp":1727678358000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/95\/1\/57\/6156158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,1]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2008,1,1]]},"published-print":{"date-parts":[[2008,1,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.6047","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2008,1]]},"published":{"date-parts":[[2008,1,1]]}}}