{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T17:44:59Z","timestamp":1781372699175,"version":"3.54.1"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2008,6,23]],"date-time":"2008-06-23T00:00:00Z","timestamp":1214179200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,7,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Sacral nerve stimulation (SNS) has better results and safety than other surgical procedures for faecal incontinence. This prospective study assessed the clinical effectiveness and costs of SNS at a single centre.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients who had experienced one or more episodes of faecal incontinence were studied for up to 5 years by continence diary, anorectal manometry and quality of life questionnaires. Direct medical costs were calculated and the cost-effectiveness of the treatment was analysed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Fifty-seven percutaneous nerve evaluations were performed in 47 patients between June 1999 and February 2006; 29 patients underwent permanent implantation. After a median follow-up of 34\u00b77 (range 2\u00b73\u201381\u00b72) months, 25 of the 29 patients had a significant reduction in incontinence episodes; 14 patients were in complete remission. At 3-year follow-up, the mean reduction in incontinence episodes was 89 per cent. No change was observed in anal manometric values. Patients reported a significant improvement in quality of life. The introduction of SNS has an incremental cost-effectiveness ratio, below the accepted Spanish threshold.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The introduction of SNS to the management of faecal incontinence within the Spanish setting is both effective and efficient.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.6140","type":"journal-article","created":{"date-parts":[[2008,6,23]],"date-time":"2008-06-23T14:01:51Z","timestamp":1214229711000},"page":"1037-1043","source":"Crossref","is-referenced-by-count":48,"title":["Clinical and cost effectiveness of sacral nerve stimulation for faecal incontinence"],"prefix":"10.1093","volume":"95","author":[{"given":"A","family":"Mu\u00f1oz-Duyos","sequence":"first","affiliation":[{"name":"Department of General Surgery, Hospital M\u00fatua de Terrassa, University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Navarro-Luna","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hospital M\u00fatua de Terrassa, University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Brosa","sequence":"additional","affiliation":[{"name":"Oblikue Consulting, Hospital Universitari del Mar, Autonomous University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J A","family":"Pando","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hospital M\u00fatua de Terrassa, University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Sitges-Serra","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hospital Universitari del Mar, Autonomous University of Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Marco-Molina","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hospital M\u00fatua de Terrassa, University of Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,6,23]]},"reference":[{"key":"2021070907423292500_bib1","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1007\/BF02150742","article-title":"Neuroanatomy of the striated muscular anal continence mechanism. 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