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The condition usually affects elderly people with underlying co-morbidities, and early recognition and appropriate management are essential to reduce the occurrence of life-threatening complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A part-systematic review was conducted. This was based on key publications focusing on advances in management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results and conclusions<\/jats:title><jats:p>Although acute colonic dilatation has been suggested to result from a functional imbalance in autonomic nerve supply, there is little direct evidence for this. Other aetiologies derived from the evolving field of neurogastroenterology remain underexplored. The rationale of treatment is to achieve prompt and effective colonic decompression. Initial management includes supportive interventions that may be followed by pharmacological therapy. Controlled clinical trials have shown that the acetylcholinesterase inhibitor neostigmine is an effective treatment with initial response rates of 60\u201390 per cent; other drugs for use in this area are in evolution. Colonoscopic decompression is successful in approximately 80 per cent of patients, with other minimally invasive strategies continuing to be developed. Surgery has thus become largely limited to those in whom complications occur. A contemporary management algorithm is provided on this basis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bjs.6480","type":"journal-article","created":{"date-parts":[[2009,2,17]],"date-time":"2009-02-17T11:18:37Z","timestamp":1234869517000},"page":"229-239","source":"Crossref","is-referenced-by-count":156,"title":["Acute colonic pseudo-obstruction"],"prefix":"10.1093","volume":"96","author":[{"given":"R","family":"De Giorgio","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine and Centro Unificato di Ricerca BioMedica Applicata, University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C H","family":"Knowles","sequence":"additional","affiliation":[{"name":"Centre for Academic Surgery, Royal London Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,2,17]]},"reference":[{"key":"2021070910363523600_bib1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1136\/bmj.2.4579.671","article-title":"Large-intestine colic due to sympathetic deprivation; a new clinical syndrome","volume":"2","author":"Ogilvie","year":"1948","journal-title":"Br Med J"},{"key":"2021070910363523600_bib2","first-page":"721","article-title":"Spastic ileus","volume":"50","author":"Zimmerman","year":"1930","journal-title":"Surg Gynecol Obstet"},{"key":"2021070910363523600_bib3","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1136\/bmj.1.4611.890","article-title":"Ogilvie's syndrome of false colonic obstruction; a case with post-mortem findings","volume":"1","author":"Dunlop","year":"1949","journal-title":"Br Med J"},{"key":"2021070910363523600_bib4","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1136\/bmj.2.3849.678","article-title":"Fatal perforation of the caecum in a case of sprue","volume":"2","author":"Low","year":"1934","journal-title":"Br Med J"},{"key":"2021070910363523600_bib5","first-page":"206","article-title":"Intestinal pseudo-obstruction","volume":"3","author":"Dudley","year":"1958","journal-title":"J R Coll Surg Edinb"},{"key":"2021070910363523600_bib6","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1136\/bmj.2.5709.583","article-title":"Pseudo-obstruction of the large bowel","volume":"2","author":"Caves","year":"1970","journal-title":"Br Med J"},{"key":"2021070910363523600_bib7","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1002\/bjs.1800611210","article-title":"Pseudo-obstruction of the large bowel","volume":"61","author":"Bardsley","year":"1974","journal-title":"Br J Surg"},{"key":"2021070910363523600_bib8","first-page":"44","article-title":"Pseudo-obstruction of the colon","volume":"133","author":"Wanebo","year":"1971","journal-title":"Surg Gynecol Obstet"},{"key":"2021070910363523600_bib9","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF02553265","article-title":"Ogilvie's syndrome (acute colonic pseudo-obstruction): review of the literature (October 1948 to March 1980) and report of four additional cases","volume":"25","author":"Nanni","year":"1982","journal-title":"Dis Colon Rectum"},{"key":"2021070910363523600_bib10","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1136\/bmj.39308.342639.AD","article-title":"Should eponyms be abandoned? 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