{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:24:17Z","timestamp":1790414657995,"version":"4.1.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2009,4,21]],"date-time":"2009-04-21T00:00:00Z","timestamp":1240272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"G\u00e4vle Hospital Research Fund"},{"name":"Regional Research Fund Uppsala\/\u00d6rebro"},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["K2007-64X-20406-01-3"],"award-info":[{"award-number":["K2007-64X-20406-01-3"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,5,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim was to investigate the association between colonic ischaemia and intra-abdominal pressure (IAP) after surgery for ruptured abdominal aortic aneurysm (rAAA).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Sigmoid colon perfusion was monitored with an intramucosal pH (pHi) tonometer. Patients with a pHi of 7\u00b71 or less were treated for suspected hypovolaemia with intravenous colloids and colonoscopy. IAP was measured every 4 h. Patients with an IAP of 20 mmHg or more had neuromuscular blockade, relaparotomy or both.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 52 consecutive patients had open rAAA repair; 30-day mortality was 27 per cent. Eight patients died shortly after surgery. Fifteen were not monitored for practical reasons; mortality in this group was 33 per cent. IAP and pHi were measured throughout the stay in intensive care in the remaining 29 patients. Monitoring led to volume resuscitation in 25 patients, neuromuscular blockade in 16, colonoscopy in 19 and relaparotomy in two. One patient died in this group. Twenty-three of 29 patients had a pHi of 7\u00b71 or less, of whom 15 had a pHi of 6\u00b79 or less. Sixteen had an IAP of 20 mmHg or more, of whom ten also had a pHi below 6\u00b790. Peak IAP values correlated with the simultaneously measured pHi (r = \u20130\u00b739, P = 0\u00b7003).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Raised IAP is an important mechanism behind colonic hypoperfusion after rAAA repair. Monitoring IAP and timely intervention may improve outcome.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.6592","type":"journal-article","created":{"date-parts":[[2009,4,21]],"date-time":"2009-04-21T14:57:05Z","timestamp":1240325825000},"page":"621-627","source":"Crossref","is-referenced-by-count":49,"title":["Colonic ischaemia and intra-abdominal hypertension following open repair of ruptured abdominal aortic aneurysm"],"prefix":"10.1093","volume":"96","author":[{"given":"K","family":"Djavani","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences, Section of Vascular Surgery, Sweden"},{"name":"Department of Surgery, G\u00e4vle County Hospital, G\u00e4vle, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Wanhainen","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Section of Vascular Surgery, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Valtysson","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care, Uppsala University Hospital, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Bj\u00f6rck","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Section of Vascular Surgery, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,4,21]]},"reference":[{"key":"2021070906273079700_bib1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1006\/jsre.1996.0056","article-title":"Ischemic colitis complicating abdominal aortic aneurysm surgery in the U.S. Veteran","volume":"60","author":"Longo","year":"1996","journal-title":"J Surg Res"},{"key":"2021070906273079700_bib2","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1078-5884(96)80098-0","article-title":"Incidence and clinical presentation of bowel ischaemia after aortoiliac surgery\u20142930 operations from a population-based registry in Sweden","volume":"12","author":"Bj\u00f6rck","year":"1996","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"2021070906273079700_bib3","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S1078-5884(97)80061-5","article-title":"Risk factors for intestinal ischaemia after aortoiliac surgery. 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