{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:04:42Z","timestamp":1782299082935,"version":"3.54.5"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim of this study was to determine the fate of the rectum, functional results and quality of life after ileorectal anastomosis (IRA) in ulcerative colitis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients with ulcerative colitis and indeterminate colitis who underwent IRA from 1971 to 2006 were evaluated retrospectively. Twenty-two patients with an IRA were matched by age, sex and follow-up duration with 66 patients with an ileal pouch\u2013anal anastomosis (IPAA) and compared for functional outcomes and quality of life.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Eighty-six patients with an IRA were included. Median follow-up was 9 (range 1\u201336) years. Rectal dysplasia and cancer rates were 17 and 8 per cent respectively. The rectum was resected in 46 patients (53 per cent) because of refractory proctitis in 24, rectal dysplasia in 15 and rectal cancer in seven. The cumulative probability of having a functioning IRA at 10 and 20 years was 74 and 46 per cent respectively. Patients with an IRA had fewer bowel movements (P = 0\u00b7020) and less night-time seepage (P = 0\u00b7020) but increased urgency (P &amp;lt; 0\u00b7001) compared with patients with an IPAA, whereas quality of life was similar.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In selected patients with ulcerative colitis IRA gives an acceptable quality of life and functional outcome that are comparable to those in patients with an IPAA. Owing to the risk of cancer, surveillance of the rectum is mandatory.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.6809","type":"journal-article","created":{"date-parts":[[2009,12,10]],"date-time":"2009-12-10T12:51:16Z","timestamp":1260449476000},"page":"65-69","source":"Crossref","is-referenced-by-count":113,"title":["Clinical outcomes of ileorectal anastomosis for ulcerative colitis"],"prefix":"10.1093","volume":"97","author":[{"given":"A","family":"da Luz Moreira","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic , Ohio,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R P","family":"Kiran","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic , Ohio,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Lavery","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic , Ohio,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,1,1]]},"reference":[{"key":"2024093006370857700_bib1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00384-003-0543-7","article-title":"Sexual function and continence after ileo pouch anal anastomosis: a comparison between a meta-analysis and a questionnaire survey","volume":"19","author":"Hueting","year":"2004","journal-title":"Int J Colorectal Dis"},{"key":"2024093006370857700_bib2","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.surg.2004.06.018","article-title":"Fertility is reduced after restorative proctocolectomy with ileal pouch anal anastomosis: a study of 300 patients","volume":"136","author":"Gorgun","year":"2004","journal-title":"Surgery"},{"key":"2024093006370857700_bib3","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1136\/gut.2005.090316","article-title":"Threefold increased risk of infertility: a meta-analysis of infertility after ileal pouch anal anastomosis in ulcerative colitis","volume":"55","author":"Waljee","year":"2006","journal-title":"Gut"},{"key":"2024093006370857700_bib4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0002-9610(85)80004-0","article-title":"Complications and quality of life after ileorectal anastomosis for ulcerative colitis","volume":"149","author":"Oakley","year":"1985","journal-title":"Am J Surg"},{"key":"2024093006370857700_bib5","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/BF02134178","article-title":"Long-term results of ileorectal anastomosis in ulcerative colitis in Stockholm County","volume":"33","author":"Leijonmarck","year":"1990","journal-title":"Dis Colon Rectum"},{"key":"2024093006370857700_bib6","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s10151-006-0286-x","article-title":"The place for colectomy and ileorectal anastomosis: a valid surgical option for ulcerative colitis?","volume":"10","author":"B\u00f6rjesson","year":"2006","journal-title":"Tech Coloproctol"},{"key":"2024093006370857700_bib7","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/145749690509400110","article-title":"Fate of the rectum after colectomy with ileorectal anastomosis in ulcerative colitis","volume":"94","author":"Lepist\u00f6","year":"2005","journal-title":"Scand J Surg"},{"key":"2024093006370857700_bib8","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1067\/msy.2002.127689","article-title":"Portal vein thrombi after restorative proctocolectomy","volume":"132","author":"Remzi","year":"2002","journal-title":"Surgery"},{"key":"2024093006370857700_bib9","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.surg.2006.07.015","article-title":"Factors associated with failure in managing pelvic sepsis after ileal pouch\u2013anal anastomosis (IPAA)\u2014a multivariate analysis","volume":"140","author":"Sagap","year":"2006","journal-title":"Surgery"},{"key":"2024093006370857700_bib10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s10350-004-6488-2","article-title":"Dysplasia of the anal transitional zone after ileal pouch\u2013anal anastomosis: results of prospective evaluation after a minimum of 10 years","volume":"46","author":"Remzi","year":"2003","journal-title":"Dis Colon Rectum"},{"key":"2024093006370857700_bib11","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1463-1318.2006.01148.x","article-title":"Risk of dysplasia and adenocarcinoma following restorative proctocolectomy for ulcerative colitis","volume":"9","author":"Das","year":"2007","journal-title":"Colorectal Dis"},{"key":"2024093006370857700_bib12","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1080\/00365521.1975.12097024","article-title":"Ileorectal anastomosis in ulcerative colitis. 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