{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:20:30Z","timestamp":1774581630506,"version":"3.50.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2010,1,12]],"date-time":"2010-01-12T00:00:00Z","timestamp":1263254400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Uppsala University, Region Sk\u00e5ne and Aarhus University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,1,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Previous studies of video-assisted techniques for parathyroidectomy in patients with primary hyperparathyroidism have found similar or better results compared with bilateral neck exploration. The aim of the present study was to compare open minimally invasive parathyroidectomy with the video-assisted technique for primary hyperparathyroidism in a multicentre randomized trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Some 143 patients were randomized to open (n = 75) or video-assisted (n = 68) parathyroidectomy after positive sestamibi scintigraphy. There were no differences in preoperative data. The open operation was performed through a 15-mm incision. The video-assisted techniques used were minimally invasive video-assisted parathyroidectomy (MIVAP) or video-assisted parathyroidectomy using the lateral approach (VAPLA). Data were collected prospectively including postoperative pain scoring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The procedure was significantly quicker for the open compared to the video assisted operations: mean(s.d.) 60(35) versus 84(47) min (P = 0\u00b7001). Both groups of patients had similar conversion rates and the same outcome, with comparable incision lengths, low scores for postoperative neck discomfort, high cosmetic satisfaction and low complication rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Open minimally invasive parathyroidectomy for primary hyperparathyroidism was quicker than either video-assisted technique. Registration number: NCT00877981 (http:\/\/www.clinicaltrials.gov)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bjs.6810","type":"journal-article","created":{"date-parts":[[2009,12,24]],"date-time":"2009-12-24T04:41:11Z","timestamp":1261629671000},"page":"177-184","source":"Crossref","is-referenced-by-count":41,"title":["Randomized clinical trial comparing open with video-assisted minimally invasive parathyroid surgery for primary hyperparathyroidism"],"prefix":"10.1093","volume":"97","author":[{"given":"O","family":"Hessman","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences, Uppsala University , Uppsala,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Westerdahl","sequence":"additional","affiliation":[{"name":"Department of Surgery, Lund University Hospital , Lund,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Al-Suliman","sequence":"additional","affiliation":[{"name":"Unit of Breast and Endocrine Surgery, Surgical Department P, Aarhus University Hospital , Aarhus,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Unit of Breast and Endocrine Surgery, Surgical Department P, Aarhus University Hospital , Aarhus,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Hellman","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Uppsala University , Uppsala,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Bergenfelz","sequence":"additional","affiliation":[{"name":"Department of Surgery, Lund University Hospital , Lund,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2010,2,1]]},"reference":[{"key":"2024093006372812600_bib1","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0140-6736(07)61213-6","article-title":"Clinical update: sporadic primary hyperparathyroidism","volume":"370","author":"Sitges-Serra","year":"2007","journal-title":"Lancet"},{"key":"2024093006372812600_bib2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/00000658-198203000-00001","article-title":"Unilateral parathyroidectomy in hyperparathyroidism due to single adenoma","volume":"195","author":"Tibblin","year":"1982","journal-title":"Ann Surg"},{"key":"2024093006372812600_bib3","first-page":"109","article-title":"Intraoperative fall in plasma levels of intact parathyroid hormone after removal of one enlarged parathyroid gland in hyperparathyroid patients","volume":"157","author":"Bergenfelz","year":"1991","journal-title":"Eur J Surg"},{"key":"2024093006372812600_bib4","first-page":"1019","article-title":"Clinical usefulness of an intraoperative \u2018quick parathyroid hormone\u2019 assay","volume":"114","author":"Irvin","year":"1993","journal-title":"Surgery"},{"key":"2024093006372812600_bib5","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1002\/bjs.1800830656","article-title":"Endoscopic subtotal parathyroidectomy in patients with primary hyperparathyroidism","volume":"83","author":"Gagner","year":"1996","journal-title":"Br J Surg"},{"key":"2024093006372812600_bib6","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/BF03347996","article-title":"Minimally invasive, video-assisted parathyroid surgery for primary hyperparathyroidism","volume":"20","author":"Miccoli","year":"1997","journal-title":"J Endocrinol Invest"},{"key":"2024093006372812600_bib7","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/s004230050207","article-title":"Minimally invasive videoscopic parathyroidectomy by lateral approach","volume":"384","author":"Henry","year":"1999","journal-title":"Langenbecks Arch Surg"},{"key":"2024093006372812600_bib8","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/00000658-200009000-00005","article-title":"One hundred consecutive minimally invasive parathyroid explorations","volume":"232","author":"Udelsman","year":"2000","journal-title":"Ann Surg"},{"key":"2024093006372812600_bib9","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1046\/j.1445-2197.2002.02310.x","article-title":"Minimally invasive parathyroidectomy using the \u2018focused\u2019 lateral approach. 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