{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:34:58Z","timestamp":1792031698770,"version":"4.4.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2010,4,20]],"date-time":"2010-04-20T00:00:00Z","timestamp":1271721600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,6,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim was to identify patient-related and operative factors that might predict the outcome of percutaneous nerve evaluation (PNE).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Demographic data (age, sex, body mass index), primary cause of incontinence, number and type of incontinence episodes, results of endoanal ultrasonography and manometry, and operative factors from 244 patients who underwent PNE for faecal incontinence were reviewed. Each factor was assessed according to the outcome, and explored by univariable and multivariable analysis to identify predictors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Some 191 patients (78\u00b73 per cent) had a successful PNE. A low amplitude of sensory threshold during PNE (odds ratio (OR) 0\u00b769 (95 per cent confidence interval 0\u00b759 to 0\u00b781); P &amp;lt; 0\u00b7001) and lead placement anterior to the sacral cortex (OR 9\u00b706 (4\u00b770 to 17\u00b745); P &amp;lt; 0\u00b7001) were positive predictive factors for successful outcome of PNE. Neither a defect nor an abnormality of either the external (OR 0\u00b788 (0\u00b739 to 1\u00b797); P = 0\u00b7749) or internal (OR 0\u00b762 (0\u00b727 to 1\u00b742); P = 0\u00b7255) anal sphincter was a negative predictive factor. Demographic variables, number of incontinence episodes and the motor response threshold did not predict outcome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>No preoperative predictor of PNE outcome could be identified. Predictors were limited to operative lead placement and sensory response during PNE.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.7028","type":"journal-article","created":{"date-parts":[[2010,4,20]],"date-time":"2010-04-20T17:57:28Z","timestamp":1271786248000},"page":"1096-1102","source":"Crossref","is-referenced-by-count":38,"title":["Predictors of the outcome of percutaneous nerve evaluation for faecal incontinence"],"prefix":"10.1093","volume":"97","author":[{"given":"Y","family":"Maeda","sequence":"first","affiliation":[{"name":"Surgical Research Unit, Aarhus University Hospital, Aarhus, Denmark"},{"name":"Physiology Unit, St Mark's Hospital, Harrow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Norton","sequence":"additional","affiliation":[{"name":"Physiology Unit, St Mark's Hospital, Harrow, UK"},{"name":"Florence Nightingale School of Nursing and Midwifery, King's College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Lundby","sequence":"additional","affiliation":[{"name":"Surgical Research Unit, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Buntzen","sequence":"additional","affiliation":[{"name":"Surgical Research Unit, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Laurberg","sequence":"additional","affiliation":[{"name":"Surgical Research Unit, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,4,20]]},"reference":[{"key":"2021070906551551400_bib1","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1007\/s10350-005-0062-4","article-title":"Sacral nerve stimulation can be successful in patients with ultrasound evidence of external anal sphincter disruption","volume":"48","author":"Conaghan","year":"2005","journal-title":"Dis Colon Rectum"},{"key":"2021070906551551400_bib2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1463-1318.2007.01319.x","article-title":"Predictive factors for successful sacral nerve stimulation in the treatment of faecal incontinence: a 10-year cohort analysis","volume":"10","author":"Dudding","year":"2008","journal-title":"Colorectal Dis"},{"key":"2021070906551551400_bib3","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1463-1318.2007.01375.x","article-title":"Is a morphologically intact anal sphincter necessary for success with sacral nerve modulation in patients with faecal incontinence?","volume":"10","author":"Melenhorst","year":"2008","journal-title":"Colorectal Dis"},{"key":"2021070906551551400_bib4","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1007\/s10350-008-9326-0","article-title":"Sacral nerve stimulation for fecal incontinence: external anal sphincter defect vs. intact anal sphincter","volume":"51","author":"Chan","year":"2008","journal-title":"Dis Colon Rectum"},{"key":"2021070906551551400_bib5","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1007\/DCR.0b013e31819f7400","article-title":"Efficacy of sacral nerve stimulation for fecal incontinence in patients with anal sphincter defects","volume":"52","author":"Boyle","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"2021070906551551400_bib6","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/DCR.0b013e3181a91241","article-title":"Can sensory and\/or motor reactions during percutaneous nerve evaluation predict outcome of sacral nerve modulation?","volume":"52","author":"Govaert","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"2021070906551551400_bib7","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF02050307","article-title":"Etiology and management of fecal incontinence","volume":"36","author":"Jorge","year":"1993","journal-title":"Dis Colon Rectum"},{"key":"2021070906551551400_bib8","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/S0140-6736(04)15999-0","article-title":"Sacral spinal nerve stimulation for faecal incontinence: multicentre study","volume":"363","author":"Matzel","year":"2004","journal-title":"Lancet"},{"key":"2021070906551551400_bib9","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s10350-004-0524-0","article-title":"Reliability of electrophysiologic anal tests in predicting the outcome of sacral nerve modulation for fecal incontinence","volume":"47","author":"Altomare","year":"2004","journal-title":"Dis Colon Rectum"},{"key":"2021070906551551400_bib10","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1007\/s10350-004-6448-x","article-title":"Fecal incontinence in females with a past history of vaginal delivery: significance of anal sphincter defects detected by ultrasound","volume":"45","author":"Damon","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"2021070906551551400_bib11","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1097\/01.sla.0000186281.09475.db","article-title":"Efficacy of sacral nerve stimulation for fecal incontinence: results of a multicenter double-blind crossover study","volume":"242","author":"Leroi","year":"2005","journal-title":"Ann Surg"},{"key":"2021070906551551400_bib12","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/S0302-2838(02)00029-5","article-title":"Alterations of cortical electrical activity in patients with sacral neuromodulator","volume":"41","author":"Braun","year":"2002","journal-title":"Eur Urol"},{"key":"2021070906551551400_bib13","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1097\/01.ju.0000181806.59363.d1","article-title":"Changes in brain activity following sacral neuromodulation for urinary retention","volume":"174","author":"Dasgupta","year":"2005","journal-title":"J Urol"},{"key":"2021070906551551400_bib14","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1111\/j.1464-410X.2006.06521.x","article-title":"Different brain effects during chronic and acute sacral neuromodulation in urge incontinent patients with implanted neurostimulators","volume":"98","author":"Blok","year":"2006","journal-title":"BJU Int"},{"key":"2021070906551551400_bib15","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/bjs.5905","article-title":"Normalization of substance P levels in rectal mucosa of patients with faecal incontinence treated successfully by sacral nerve stimulation","volume":"95","author":"Gooneratne","year":"2008","journal-title":"Br J Surg"}],"container-title":["British Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.7028","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/97\/7\/1096\/36655984\/bjs7028.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/bjs\/article-pdf\/97\/7\/1096\/36655984\/bjs7028.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T15:53:37Z","timestamp":1625846017000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/97\/7\/1096\/6150524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,20]]},"references-count":15,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2010,4,20]]},"published-print":{"date-parts":[[2010,6,2]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.7028","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2010,7]]},"published":{"date-parts":[[2010,4,20]]}}}