{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:21:13Z","timestamp":1740126073961,"version":"3.37.3"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2010,4,28]],"date-time":"2010-04-28T00:00:00Z","timestamp":1272412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001530","name":"Canterbury Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001530","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Canterbury Gastroenterology Research Trust"},{"name":"Bowel and Liver Trust, Canterbury"},{"name":"New Zealand Society of Gastroenterology"},{"name":"Canterbury Liver and Digestive Diseases Trust"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,6,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The aim of this study was describe the frequency and characteristics of perianal surgical intervention (PSI) for Crohn's disease in a population-based cohort of patients with inflammatory bowel disease (IBD).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A total of 1421 patients with IBD were recruited, representing approximately 91 per cent of people with IBD in Canterbury, New Zealand. The clinical notes were screened to confirm the diagnosis and extract clinical data, including details of PSIs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Some 649 patients with Crohn's disease were included in the analysis, of whom 119 (18\u00b73 per cent) had at least one PSI. Of these, 61 (51\u00b73 per cent) required further procedures. Operations for perianal abscess and fistula accounted for 72\u00b74 per cent of interventions. PSI rates did not differ between the sexes (P = 0\u00b7218). Age less than 17 years (adjusted odds ratio (OR) 1\u00b789 (95 per cent confidence interval 1\u00b708 to 3\u00b728)) and ileal disease (OR 1\u00b776 (1\u00b706 to 2\u00b792)) were identified as predictors of PSI. As disease duration increased, so did the proportion of patients with complicated intestinal disease among those who had undergone PSI. The median time to first PSI from diagnosis of Crohn's disease was 28 (interquartile range 7\u201382) months. Sex, age at diagnosis and disease location did not influence the time to first PSI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>PSIs are frequent in patients with Crohn's disease, particularly those with ileal disease and those diagnosed at a young age.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.7031","type":"journal-article","created":{"date-parts":[[2010,4,29]],"date-time":"2010-04-29T09:02:05Z","timestamp":1272531725000},"page":"1103-1109","source":"Crossref","is-referenced-by-count":14,"title":["Ileal disease is associated with surgery for perianal disease in a population-based Crohn's disease cohort"],"prefix":"10.1093","volume":"97","author":[{"given":"T","family":"Eglinton","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Otago, New Zealand"},{"name":"Department of Colorectal Surgery, Christchurch Hospital, Christchurch, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Reilly","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Otago, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Otago, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Barclay","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Otago, New Zealand"},{"name":"Department of Gastroenterology, Christchurch Hospital, Christchurch, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Frizelle","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Otago, New Zealand"},{"name":"Department of Colorectal Surgery, Christchurch Hospital, Christchurch, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Gearry","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Otago, New Zealand"},{"name":"Department of Gastroenterology, Christchurch Hospital, Christchurch, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2010,4,28]]},"reference":[{"key":"2021070906553044100_bib1","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1097\/00000658-193811000-00007","article-title":"Perianal fistulae as a complication of regional ileitis","volume":"108","author":"Penner","year":"1938","journal-title":"Ann Surg"},{"key":"2021070906553044100_bib2","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1053\/j.gastro.2005.12.019","article-title":"Predictors of Crohn's disease","volume":"130","author":"Beaugerie","year":"2006","journal-title":"Gastroenterology"},{"key":"2021070906553044100_bib3","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1007\/s10350-007-9006-5","article-title":"Long-term quality of life in patients with Crohn's disease and perianal fistulas: influence of fecal diversion","volume":"50","author":"Kasparek","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"2021070906553044100_bib4","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1002\/bjs.4613","article-title":"Perianal Crohn's disease","volume":"91","author":"Singh","year":"2004","journal-title":"Br J Surg"},{"key":"2021070906553044100_bib5","first-page":"581","article-title":"Management of fistula-in-ano: 1990 Roussel Lecture","volume":"34","author":"McLeod","year":"1991","journal-title":"Can J Surg"},{"key":"2021070906553044100_bib6","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/BF02058706","article-title":"Perianal Crohn's disease. 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