{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T10:51:13Z","timestamp":1792320673217,"version":"4.4.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2010,5,19]],"date-time":"2010-05-19T00:00:00Z","timestamp":1274227200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,6,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Reflux control may be ineffective in a substantial number of patients after endoluminal EsophyX\u00ae fundoplication for gastro-oesophageal reflux disease. Subsequent laparoscopic Nissen fundoplication (LNF) might be required to relieve symptoms. The aim of this study was to evaluate the outcome of LNF after previous EsophyX\u00ae fundoplication.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>EsophyX\u00ae failure was defined as recurrence or persistence of typical symptoms, with or without anatomical failure of the wrap or persisting pathological oesophageal acid exposure. Consecutive patients who underwent LNF after failed EsophyX\u00ae fundoplication were identified. Symptomatic outcome was obtained by standardized questionnaire, and objective outcome by endoscopy, oesophageal manometry and pH monitoring.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Eleven patients were included. During LNF, intraoperative gastric perforation occurred in two patients and one developed a subphrenic abscess after operation. Daily heartburn was present in one patient after LNF and three had troublesome daily dysphagia. General quality of life after LNF was not significantly better than that before EsophyX\u00ae fundoplication. Oesophageal acid exposure was normalized in all patients after surgery. Oesophagitis was absent after LNF in all except one patient who had persisting grade A oesophagitis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Symptomatic and objective reflux control are satisfactory after LNF for a failed EsophyX\u00ae procedure. Previous EsophyX\u00ae fundoplication, however, is associated with a risk of gastric injury during LNF and a relatively high rate of postfundoplication dysphagia.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.7078","type":"journal-article","created":{"date-parts":[[2010,5,20]],"date-time":"2010-05-20T09:48:30Z","timestamp":1274348910000},"page":"1051-1055","source":"Crossref","is-referenced-by-count":29,"title":["Laparoscopic Nissen fundoplication after failed EsophyX\u00ae fundoplication"],"prefix":"10.1093","volume":"97","author":[{"given":"E J B","family":"Furn\u00e9e","sequence":"first","affiliation":[{"name":"Department of Surgery, University Medical Centre, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J A J L","family":"Broeders","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Medical Centre, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W A","family":"Draaisma","sequence":"additional","affiliation":[{"name":"Department of Surgery, Meander Medical Centre, Amersfoort, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M P","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Meander Medical Centre, Amersfoort, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E J","family":"Hazebroek","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Medical Centre, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A J P M","family":"Smout","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Medical Centre, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P J J","family":"van Rijn","sequence":"additional","affiliation":[{"name":"Department of Surgery, Lange Land Hospital, Zoetermeer, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I A M J","family":"Broeders","sequence":"additional","affiliation":[{"name":"Department of Surgery, Meander Medical Centre, Amersfoort, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,5,19]]},"reference":[{"key":"2021070906552690800_bib1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/bjs.6440","article-title":"Systematic review of endoscopic treatments for gastro-oesophageal reflux disease","volume":"96","author":"Chen","year":"2009","journal-title":"Br J Surg"},{"key":"2021070906552690800_bib2","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00001610-200201000-00005","article-title":"Endoluminal gastroplication. 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