{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:49:14Z","timestamp":1792093754115,"version":"4.4.0"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2011,1,19]],"date-time":"2011-01-19T00:00:00Z","timestamp":1295395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Incisional hernia is a frequent complication of abdominal surgery, often requiring surgical intervention. This prospective randomized trial compared suture materials for closure of the fascia after abdominal surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 456 patients the abdominal fascia was closed with either non-absorbable (polypropylene; Prolene\u00ae) or absorbable (polydioxanone; PDS\u00ae) suture material. Follow-up was by clinical examination and ultrasonography at 6-month intervals. Outcome measures were incisional hernia, surgical-site infection and suture sinus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Some 223 patients were analysed after closure with Prolene\u00ae and 233 after PDS\u00ae. Median follow-up was 32 and 31 months respectively. There was no significant difference in the incidence of incisional hernia between the groups: 20\u00b72 per cent (45 of 223) for Prolene\u00ae and 24\u00b79 per cent (58 of 233) with PDS\u00ae (P = 0\u00b7229). Kaplan-Meier analysis showed a cumulative rate after 4 years of 23\u00b77 and 30\u00b72 per cent for Prolene\u00ae and PDS\u00ae respectively (P = 0\u00b7222). Secondary outcome measures showed no significant differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of incisional hernia in both groups was higher than expected from previous literature. There were no significant differences between the two suture methods. Registration number: ISRCTN65599814 (http:\/\/www.clinical-trials.com).<\/jats:p><\/jats:sec>","DOI":"10.1002\/bjs.7398","type":"journal-article","created":{"date-parts":[[2011,1,19]],"date-time":"2011-01-19T14:57:26Z","timestamp":1295449046000},"page":"633-639","source":"Crossref","is-referenced-by-count":79,"title":["Randomized clinical trial comparing polypropylene or polydioxanone for midline abdominal wall closure"],"prefix":"10.1093","volume":"98","author":[{"given":"A","family":"Bloemen","sequence":"first","affiliation":[{"name":"Department of General Surgery, Orbis Medical Centre, PO Box 5500, 6130 MB Sittard, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"van Dooren","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Orbis Medical Centre, PO Box 5500, 6130 MB Sittard, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B F","family":"Huizinga","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Orbis Medical Centre, PO Box 5500, 6130 MB Sittard, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A G M","family":"Hoofwijk","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Orbis Medical Centre, PO Box 5500, 6130 MB Sittard, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,1,19]]},"reference":[{"key":"2021070906354508300_bib1","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/00000658-200003000-00018","article-title":"The search for an ideal method of abdominal fascial closure: a meta-analysis","volume":"231","author":"Hodgson","year":"2000","journal-title":"Ann Surg"},{"key":"2021070906354508300_bib2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1007\/s00104-002-0425-5","article-title":"[Factors influencing the development of incisional hernia. 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