{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T14:24:56Z","timestamp":1772807096048,"version":"3.50.1"},"reference-count":53,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T00:00:00Z","timestamp":1302134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,5,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Most patients with gallbladder and common bile duct stones are treated by preoperative endoscopic sphincterotomy (POES) followed by laparoscopic cholecystectomy. Recently, intraoperative endoscopic sphincterotomy (IOES) during laparoscopic cholecystectomy has been suggested as an alternative treatment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Data from randomized clinical trials related to safety and effectiveness of IOES versus POES were extracted by two independent reviewers. Risk ratios (RRs) or mean differences were calculated with 95 per cent confidence intervals based on intention-to-treat analysis whenever possible.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Four trials with 532 patients comparing IOES with POES were included. There were no deaths. There was no significant difference in rates of ampullary cannulation (RR 1\u00b701, 0\u00b797 to 1\u00b704; P = 0\u00b770) or stone clearance by ES (RR 0\u00b799, 0\u00b796 to 1\u00b702; P = 0\u00b758) between the groups. The proportion of patients with at least one post-ES complication, including pancreatitis, bleeding, perforation, cholangitis, cholecystitis or gastric ulcer, was significantly lower in the IOES group (RR 0\u00b737, 0\u00b718 to 0\u00b778; P = 0\u00b7009). There was no significant difference in morbidity after laparoscopic cholecystectomy or requirement for open operation between the groups. Mean hospital stay was 3 days shorter in the IOES group: mean difference \u2212 2\u00b783 (\u22123\u00b766 to \u2212 2\u00b700) days (P &amp;lt; 0\u00b7001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In patients with gallbladder and common bile duct stones, IOES is as effective and safe as POES and results in a significantly shorter hospital stay.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.7460","type":"journal-article","created":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T23:50:13Z","timestamp":1302220213000},"page":"908-916","source":"Crossref","is-referenced-by-count":59,"title":["Systematic review and meta-analysis of intraoperative <i>versus<\/i> preoperative endoscopic sphincterotomy in patients with gallbladder and suspected common bile duct stones"],"prefix":"10.1093","volume":"98","author":[{"given":"K","family":"Gurusamy","sequence":"first","affiliation":[{"name":"Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free Campus, University College London Medical School, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S J","family":"Sahay","sequence":"additional","affiliation":[{"name":"Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free Campus, University College London Medical School, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A K","family":"Burroughs","sequence":"additional","affiliation":[{"name":"Liver Unit, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B R","family":"Davidson","sequence":"additional","affiliation":[{"name":"Hepatopancreatobiliary and Liver Transplant Surgery, University Department of Surgery, Royal Free Campus, University College London Medical School, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,4,7]]},"reference":[{"key":"2021070910494602300_bib1","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1093\/oxfordjournals.aje.a113800","article-title":"Prevalence of gallstone disease in an Italian adult female population","volume":"119","author":"Rome Group for the Epidemiology and Prevention of Cholelithiasis (GREPCO)","year":"1984","journal-title":"Am J Epidemiol"},{"key":"2021070910494602300_bib2","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1002\/hep.1840080433","article-title":"The epidemiology of gallstone disease in Rome, Italy. 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