{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:38:06Z","timestamp":1781311086424,"version":"3.54.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2011,5,27]],"date-time":"2011-05-27T00:00:00Z","timestamp":1306454400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Randomized trials suggest that division of the short gastric vessels during Nissen fundoplication is unnecessary. Some trials report an increased risk of gas bloat symptoms following division of the short gastric vessels. In this study long-term follow-up data from the two largest randomized clinical trials of division versus no division of the short gastric vessels during laparoscopic Nissen fundoplication were combined to determine whether there were differences in late outcome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients with gastro-oesophageal reflux disease who underwent primary laparoscopic antireflux surgery and were included in two previously reported randomized trials were studied. Of 99 patients enrolled in the Swedish study and 102 in the Australian study, the short gastric vessels were divided in 104 and left intact in 97. Data sets were combined and late clinical outcomes analysed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>At 10\u201312 years' follow-up (mean 11\u00b75 years) clinical data were obtained from 170 patients (86 with vessels divided, 84 undivided). Statistical analysis of the combined data set showed no significant differences in symptoms of heartburn or dysphagia, ability to belch or vomit, and use of antisecretory medications. Division of the short gastric vessels was associated with a higher rate of bloating symptoms (72 versus 48 per cent; P = 0\u00b7002).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Division of the short gastric vessels is followed by a slightly poorer clinical outcome at late follow-up after Nissen fundoplication. Surgeons should avoid dividing these vessels when undertaking a laparoscopic Nissen fundoplication.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.7563","type":"journal-article","created":{"date-parts":[[2011,5,27]],"date-time":"2011-05-27T13:49:12Z","timestamp":1306504152000},"page":"1063-1067","source":"Crossref","is-referenced-by-count":37,"title":["Meta-analysis of two randomized controlled trials to identify long-term symptoms after division of the short gastric vessels during Nissen fundoplication"],"prefix":"10.1093","volume":"98","author":[{"given":"C","family":"Engstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Surgery, Sahlgrenska University Hospital, G\u00f6teborg, Sweden"},{"name":"Flinders University Department of Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G G","family":"Jamieson","sequence":"additional","affiliation":[{"name":"Adelaide University Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P G","family":"Devitt","sequence":"additional","affiliation":[{"name":"Adelaide University Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D I","family":"Watson","sequence":"additional","affiliation":[{"name":"Flinders University Department of Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,5,27]]},"reference":[{"key":"2021070906574937500_bib1","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1002\/bjs.1800830633","article-title":"Long-term results of a prospective randomized comparison of total fundic wrap (Nissen\u2013Rossetti) or semifundoplication (Toupet) for gastroesophageal reflux","volume":"83","author":"Lundell","year":"1996","journal-title":"Br J Surg"},{"key":"2021070906574937500_bib2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/01.sla.0000263508.53334.af","article-title":"Comparison of long-term outcome of laparoscopic and conventional Nissen fundoplication: a prospective randomized study with an 11-year follow-up","volume":"246","author":"Salminen","year":"2007","journal-title":"Ann Surg"},{"key":"2021070906574937500_bib3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1046\/j.1365-2168.1999.00969.x","article-title":"Prospective randomized double-blind trial between laparoscopic Nissen fundoplication and anterior partial fundoplication","volume":"86","author":"Watson","year":"1999","journal-title":"Br J Surg"},{"key":"2021070906574937500_bib4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/01.sla.0000080821.08262.53","article-title":"Efficacy of an anterior as compared with posterior laparoscopic partial fundoplication: result of a randomized clinical trial","volume":"238","author":"Hagedorn","year":"2003","journal-title":"Ann Surg"},{"key":"2021070906574937500_bib5","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1445-2197.2010.05377.x","article-title":"Changing work patterns for benign upper gastrointestinal and biliary disease; 1994\u20132007","volume":"80","author":"Jay","year":"2010","journal-title":"ANZ J Surg"},{"key":"2021070906574937500_bib6","volume-title":"Dyspepsi och reflux. 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