{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T17:33:04Z","timestamp":1788975184491,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2011,10,21]],"date-time":"2011-10-21T00:00:00Z","timestamp":1319155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,10,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Liver ischaemia after pancreatic resection is a rare but potentially serious complication. The aim of this study was to determine the impact of postoperative liver ischaemia after pancreatic resection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>All consecutive patients undergoing pancreatic resection between January 2007 and August 2008 in the Department of Surgery in Heidelberg were identified retrospectively from a prospectively collected database and analysed with a focus on postoperative hepatic perfusion failure. Laboratory data, computed tomography (CT) findings, symptoms, therapy and outcome were recorded.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 762 patients underwent pancreatic resection in the study period. Seventeen patients (2\u00b72 per cent) with a postoperative increase in liver enzymes underwent contrast-enhanced CT for suspected liver perfusion failure. The types of perfusion failure were hypoperfusion without occlusion of major hepatic vessels (6 patients) and ischaemia with arterial (5) and\/or portal vein (6) involvement. The overall mortality rate was 29 per cent (5 of 17 patients). Therapy included conservative treatment (7), radiological or surgical revascularization and necrosectomy or resection of necrotic liver tissue (10). Outcome varied from full recovery (4 patients) to moderate systemic complications (6) and severe complications (7) including death. Simultaneous involvement of the portal vein and hepatic artery was always fatal.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Postoperative liver perfusion failure is a rare but potentially severe complication following pancreatic surgery requiring immediate recognition and, if necessary, radiological or surgical intervention.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.7675","type":"journal-article","created":{"date-parts":[[2011,10,21]],"date-time":"2011-10-21T12:44:28Z","timestamp":1319201068000},"page":"1760-1765","source":"Crossref","is-referenced-by-count":48,"title":["Clinical significance of liver ischaemia after pancreatic resection"],"prefix":"10.1093","volume":"98","author":[{"given":"T","family":"Hackert","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Heidelberg, Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U","family":"Stampfl","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Heidelberg, Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Schulz","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Heidelberg, Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Strobel","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Heidelberg, Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M W","family":"B\u00fcchler","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Heidelberg, Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Werner","sequence":"additional","affiliation":[{"name":"Department of Surgery, University 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