{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T12:42:48Z","timestamp":1784292168857,"version":"3.55.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2012,1,6]],"date-time":"2012-01-06T00:00:00Z","timestamp":1325808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Sentinel lymph node (SLN) biopsy has replaced axillary lymph node dissection (ALND) as the standard axillary staging procedure in breast cancer. Follow-up studies in SLN-negative women treated without ALND report low rates of axillary recurrence, but most studies have short follow-up, and few are multicentre studies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Between September 2000 and January 2004, patients who were SLN-negative and did not have ALND were included in a prospective cohort. Kaplan-Meier estimates were used to analyse the rates of axillary recurrence and survival. The risk of axillary recurrence was also compared in centres with high and low experience with the SLN biopsy (SLNB) technique.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 2195 patients with 2216 breast tumours were followed for a median of 65 months. Isolated axillary recurrence was diagnosed in 1\u00b70 per cent of patients. The event-free 5-year survival rate was 88\u00b78 per cent and the overall 5-year survival rate 93\u00b71 per cent. There was no difference in recurrence rates between centres contributing fewer than 150 SLNB procedures to the cohort and centres contributing 150 or more procedures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This study confirmed the low risk of axillary recurrence 5 years after SLNB for breast cancer without ALND.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.7820","type":"journal-article","created":{"date-parts":[[2011,12,19]],"date-time":"2011-12-19T12:45:01Z","timestamp":1324298701000},"page":"226-231","source":"Crossref","is-referenced-by-count":31,"title":["Axillary recurrence rate 5 years after negative sentinel node biopsy for breast cancer"],"prefix":"10.1093","volume":"99","author":[{"given":"Y","family":"Andersson","sequence":"first","affiliation":[{"name":"Department of Surgery, Central Hospital , V\u00e4ster\u00e5s,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"de Boniface","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery, Karolinska Institute, Karolinska University Hospital Solna , Stockholm,","place":["Sweden"]},{"name":"Department of Endocrine and Breast Surgery, Karolinska University Hospital Solna , Stockholm,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P-E","family":"J\u00f6nsson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Helsingborg Hospital , Helsingborg,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Ingvar","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital , Lund,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Liljegren","sequence":"additional","affiliation":[{"name":"Department of Surgery and Centre for Assessment of Medical Technology \u00d6rebro, University Hospital , \u00d6rebro,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Bergkvist","sequence":"additional","affiliation":[{"name":"Department of Surgery, Central Hospital , V\u00e4ster\u00e5s,","place":["Sweden"]},{"name":"Centre for Clinical Research, Uppsala University, Central Hospital , V\u00e4ster\u00e5s,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Frisell","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery, Karolinska Institute, Karolinska University Hospital Solna , Stockholm,","place":["Sweden"]},{"name":"Department of Endocrine and Breast Surgery, Karolinska University Hospital Solna , Stockholm,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,2,1]]},"reference":[{"key":"2024092904571740900_bib1","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1097\/00000658-199409000-00015","article-title":"Lymphatic mapping and sentinel lymphadenectomy for breast cancer","volume":"220","author":"Giuliano","year":"1994","journal-title":"Ann Surg"},{"key":"2024092904571740900_bib2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0960-7404(93)90064-6","article-title":"Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe","volume":"2","author":"Krag","year":"1993","journal-title":"Surg Oncol"},{"key":"2024092904571740900_bib3","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1007\/s002590050572","article-title":"Lymphatic mapping and sentinel lymph node biopsy in breast cancer","volume":"26","author":"Nieweg","year":"1999","journal-title":"Eur J Nucl Med"},{"key":"2024092904571740900_bib4","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1002\/bjs.5052","article-title":"Multicentre validation study of sentinel node biopsy for staging in breast cancer","volume":"92","author":"Bergkvist","year":"2005","journal-title":"Br J Surg"},{"key":"2024092904571740900_bib5","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/bjs.5992","article-title":"Second thoughts on sentinel lymph node biopsy in node-negative breast cancer","volume":"95","author":"Kuijt","year":"2008","journal-title":"Br J Surg"},{"key":"2024092904571740900_bib6","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/SLA.0b013e31812e6a73","article-title":"GIVOM Trialists. 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