{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T04:19:18Z","timestamp":1791519558412,"version":"4.3.4"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2012,1,27]],"date-time":"2012-01-27T00:00:00Z","timestamp":1327622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,4,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This was a population-based cohort study to determine the incidence, prevalence and risk factors for peritoneal carcinomatosis (PC) from colorectal cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospectively collected data were obtained from the Regional Quality Registry. The Cox proportional hazards regression model was used for multivariable analysis of clinicopathological factors to determine independent predictors of PC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All 11 124 patients with colorectal cancer in Stockholm County during 1995\u20132007 were included and followed until 2010. In total, 924 patients (8\u00b73 per cent) had synchronous or metachronous PC. PC was the first and only localization of metastases in 535 patients (4\u00b78 per cent). The prevalence of synchronous PC was 4\u00b73 per cent (477 of 11 124). The cumulative incidence of metachronous PC was 4\u00b72 per cent (447 of 10 646). Independent predictors for metachronous PC were colonic cancer (hazard ratio (HR) 1\u00b777, 95 per cent confidence interval 1\u00b731 to 2\u00b739; P = 0\u00b7002 for right-sided colonic cancer), advanced tumour (T) status (HR 9\u00b798, 3\u00b710 to 32\u00b711; P &amp;lt; 0\u00b7001 for T4), advanced node (N) status (HR 7\u00b741, 4\u00b778 to 11\u00b751; P &amp;lt; 0\u00b7001 for N2 with fewer than 12 lymph nodes examined), emergency surgery (HR 2\u00b711, 1\u00b766 to 2\u00b769; P &amp;lt; 0\u00b7001) and non-radical resection of the primary tumour (HR 2\u00b775, 2\u00b710 to 3\u00b761; P &amp;lt; 0\u00b7001 for R2 resection). Patients aged &amp;gt; 70 years had a decreased risk of metachronous PC (HR 0\u00b769, 0\u00b755 to 0\u00b787; P = 0\u00b7003).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PC is common in patients with colorectal cancer and is associated with identifiable risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bjs.8679","type":"journal-article","created":{"date-parts":[[2012,1,27]],"date-time":"2012-01-27T17:10:33Z","timestamp":1327684233000},"page":"699-705","source":"Crossref","is-referenced-by-count":453,"title":["Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer"],"prefix":"10.1093","volume":"99","author":[{"given":"J","family":"Segelman","sequence":"first","affiliation":[{"name":"Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, 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