{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:37:03Z","timestamp":1783543023552,"version":"3.55.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T00:00:00Z","timestamp":1359936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Repair of an abdominal aortic aneurysm (AAA) is undertaken to prevent rupture. Intervention is by either open repair (OR) or a more minimally invasive endovascular repair (EVAR). Quality-of-life (QoL) analysis is an important health outcome and a number of single studies have assessed QoL following OR and EVAR. This was a meta-analysis of published studies to assess the effect of an intervention on QoL in patients with an AAA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic literature search was undertaken for studies prospectively reporting QoL analysis in patients with an AAA undergoing elective intervention. A multivariable meta-analysis model was developed in which the outcomes were mean changes in QoL scores over time, both for all AAA repairs (OR and EVAR) and comparing OR with EVAR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data were collated from 16 studies (14 OR, 12 EVAR). The results suggested that treating an AAA had an effect on patient-reported QoL, evident from the statistically significant changes predominantly in domains assessing physical ability and pain. QoL was affected most within the first 3 months after any form of intervention, and was more pronounced following OR. Furthermore, a deterioration in the Physical Component Summary score following an AAA repair (either OR or EVAR) was evident at 12 months after intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Treating an AAA deleteriously affects patient-reported QoL over the first year following intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bjs.9018","type":"journal-article","created":{"date-parts":[[2012,12,19]],"date-time":"2012-12-19T06:37:36Z","timestamp":1355899056000},"page":"448-455","source":"Crossref","is-referenced-by-count":36,"title":["Meta-analysis of prospective trials determining the short- and mid-term effect of elective open and endovascular repair of abdominal aortic aneurysms on quality of life"],"prefix":"10.1093","volume":"100","author":[{"given":"P A","family":"Coughlin","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, Addenbrooke's Hospital , Leeds,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Jackson","sequence":"additional","affiliation":[{"name":"Medical Research Council Biostatistics Unit , Cambridge, Leeds,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A D","family":"White","sequence":"additional","affiliation":[{"name":"Leeds Vascular Institute , Leeds,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M A","family":"Bailey","sequence":"additional","affiliation":[{"name":"Leeds Vascular Institute , Leeds,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Farrow","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Leeds General Infirmary , Leeds,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D J A","family":"Scott","sequence":"additional","affiliation":[{"name":"Leeds Vascular Institute , Leeds,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S J","family":"Howell","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Leeds General Infirmary , Leeds,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,3,1]]},"reference":[{"key":"2024092904573070300_bib1","author":"NHS Abdominal Aortic Aneurysm Screening Programme","year":"2012"},{"key":"2024092904573070300_bib2","first-page":"100","volume-title":"International Health Conference, New York, 19\u201322 June","author":"Preamble to the Constitution of the World Health Organization","year":"1946"},{"key":"2024092904573070300_bib3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0021-9681(87)90019-1","article-title":"Utility approach to measuring health-related quality of life","volume":"40","author":"Torrance","year":"1987","journal-title":"J Chronic Dis"},{"key":"2024092904573070300_bib4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1053\/j.semvascsurg.2010.05.009","article-title":"Interpretation of the results of OVER in the context of EVAR trial, DREAM, and the EUROSTAR registry","volume":"23","author":"Malas","year":"2010","journal-title":"Semin Vasc Surg"},{"key":"2024092904573070300_bib5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36). 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