{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:17:14Z","timestamp":1790835434797,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T00:00:00Z","timestamp":1407715200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1022752"],"award-info":[{"award-number":["1022752"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1020955"],"award-info":[{"award-number":["1020955"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1019921"],"award-info":[{"award-number":["1019921"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1000967"],"award-info":[{"award-number":["1000967"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Abdominal aortic aneurysm (AAA) is an important cause of sudden death; however, there are currently incomplete means to predict the risk of AAA rupture. AAA peak wall stress (PWS) can be estimated using finite element analysis (FEA) methods from computed tomography (CT) scans. The question is whether AAA PWS can predict AAA rupture. The aim of this systematic review was to compare PWS in patients with ruptured and intact AAA.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The MEDLINE database was searched on 25 May 2013. Case\u2013control studies assessing PWS in asymptomatic intact, and acutely symptomatic or ruptured AAA from CT scans using FEA were included. Data were extracted independently. A random-effects model was used to calculate standard mean differences (SMDs) for PWS measurements.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Nine studies assessing 348 individuals were identified and used in the meta-analysis. Results from 204 asymptomatic intact and 144 symptomatic or ruptured AAAs showed that PWS was significantly greater in the symptomatic\/ ruptured AAAs compared with the asymptomatic intact AAAs (SMD 0\u00b795, 95 per cent confidence interval 0\u00b771 to 1\u00b718; P &amp;lt; 0\u00b7001). The findings remained significant after adjustment for mean systolic blood pressure, standardized at 120 mmHg (SMD 0\u00b768, 0\u00b739 to 0\u00b796; P &amp;lt; 0\u00b7001). Minimal heterogeneity between studies was noted (I2 = 0 per cent).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This study suggests that PWS is greater in symptomatic or ruptured AAA than in asymptomatic intact AAA.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.9578","type":"journal-article","created":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T00:09:33Z","timestamp":1422576573000},"page":"1350-1357","source":"Crossref","is-referenced-by-count":103,"title":["Meta-analysis of peak wall stress in ruptured, symptomatic and intact abdominal aortic aneurysms"],"prefix":"10.1093","volume":"101","author":[{"given":"S","family":"Khosla","sequence":"first","affiliation":[{"name":"Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D R","family":"Morris","sequence":"additional","affiliation":[{"name":"Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J V","family":"Moxon","sequence":"additional","affiliation":[{"name":"Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P J","family":"Walker","sequence":"additional","affiliation":[{"name":"School of Medicine and Centre for Clinical Research, University of Queensland, and Department of Vascular Surgery, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T C","family":"Gasser","sequence":"additional","affiliation":[{"name":"Department of Solid Mechanics, School of Engineering Sciences, Royal Institute of Technology, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Golledge","sequence":"additional","affiliation":[{"name":"Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Australia"},{"name":"Department of Vascular and Endovascular Surgery, Townsville Hospital, Townsville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,8,11]]},"reference":[{"key":"2021031617194859400_bjs9578-bib-0001","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ejvs.2010.09.011","article-title":"Management of abdominal aortic aneurysms clinical practice guidelines of the European Society for Vascular Surgery","volume":"41","author":"Moll","year":"2011","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"2021031617194859400_bjs9578-bib-0002","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.atherosclerosis.2011.03.006","article-title":"Current status of medical management for abdominal aortic aneurysm","volume":"217","author":"Golledge","year":"2011","journal-title":"Atherosclerosis"},{"key":"2021031617194859400_bjs9578-bib-0003","first-page":"649","article-title":"Aneurysm Trial Participants. 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