{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T01:15:19Z","timestamp":1749604519880},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2014,7,16]],"date-time":"2014-07-16T00:00:00Z","timestamp":1405468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Sacral nerve stimulation (SNS) is effective for some patients with faecal incontinence. Before insertion of a costly implant, percutaneous nerve evaluation (PNE) is undertaken to identify patients likely to report success from SNS. The aim of this study was to determine whether variables of anal sphincter function measured by anal acoustic reflectometry (AAR) could predict the outcome of PNE for faecal incontinence.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Women with faecal incontinence undergoing PNE were recruited. AAR, followed by anal manometry, was performed on the day of surgery, immediately before PNE. The outcome of PNE was determined by bowel diary results and incontinence severity score. Patients with a successful PNE outcome were compared with those with an unsuccessful outcome; logistic regression analysis was used to identify any independent predictors of success.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Fifty-two patients were recruited, of whom 32 (62 per cent) had a successful PNE outcome and 20 (38 per cent) an unsuccessful outcome. The AAR variable opening pressure was significantly greater in patients who subsequently had a successful PNE result compared with the pressure in patients who did not (28 versus 17 cmH2O; P = 0\u00b7008). No difference was seen in the manometric equivalent, maximum resting pressure. Opening pressure was an independent predictor of success with an odds ratio of 1\u00b708 (95 per cent confidence interval 1\u00b701 to 1\u00b716; P = 0\u00b7018).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>AAR is a sensitive test of sphincter function and can identify differences between patients who respond to PNE and those who do not. Opening pressure is an independent predictor of success in PNE, and may be of value in the selection of patients for this expensive treatment option.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.9586","type":"journal-article","created":{"date-parts":[[2014,7,16]],"date-time":"2014-07-16T11:29:18Z","timestamp":1405510158000},"page":"1310-1316","source":"Crossref","is-referenced-by-count":8,"title":["Anal acoustic reflectometry predicts the outcome of percutaneous nerve evaluation for faecal incontinence"],"prefix":"10.1093","volume":"101","author":[{"given":"B R","family":"Hornung","sequence":"first","affiliation":[{"name":"Pelvic Floor Service, Department of General Surgery, University Hospital South Manchester, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G L","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Salford Royal NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P J","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Surgery, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Klarskov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Herlev University Hospital, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Lose","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Herlev University Hospital, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K J","family":"Telford","sequence":"additional","affiliation":[{"name":"Pelvic Floor Service, Department of General Surgery, University Hospital South Manchester, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E S","family":"Kiff","sequence":"additional","affiliation":[{"name":"Pelvic Floor Service, Department of General Surgery, University Hospital South Manchester, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,7,16]]},"reference":[{"key":"2021031618012336100_bjs9586-bib-0001","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1053\/j.gastro.2009.04.054","article-title":"Pelvic Floor Disorders Network. 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