{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T01:58:42Z","timestamp":1774576722680,"version":"3.50.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T00:00:00Z","timestamp":1410825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001868","name":"the National Science Council, Taiwan","doi-asserted-by":"crossref","award":["NSC 102-2314-B-038-021-MY3"],"award-info":[{"award-number":["NSC 102-2314-B-038-021-MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,10,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Limited information is available on the association between a medical history of stroke and postoperative outcomes. This study investigated the outcomes following non-neurological surgery in patients with previous stroke.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Using Taiwan's National Health Insurance Research Database, a nationwide cohort study was conducted of patients who underwent non-neurological surgery between 2008 and 2010 with a medical history of stroke in the 24-month period before operation. Patients who had non-neurological surgeries without previous stroke were selected as controls by the propensity score-matched pair method. Thirty-day postoperative complications and in-hospital mortality were compared between the two groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Some 1 426 795 adults underwent major inpatient non-neurological surgery, of whom 45 420 had a medical history of previous stroke. Patients with previous stroke who underwent surgery had an increased risk of postoperative pneumonia, septicaemia, acute renal failure, acute myocardial infarction, pulmonary embolism and 30-day in-hospital mortality (adjusted rate ratio (RR) 1\u00b779, 95 per cent c.i. 1\u00b761 to 1\u00b799). Compared with controls, patients with previous stroke due to intracerebral haemorrhage (RR 3\u00b741, 2\u00b797 to 3\u00b791), and those who were treated in intensive care (RR 2\u00b755, 2\u00b724 to 2\u00b790) or underwent neurosurgery (RR 2\u00b749, 2\u00b712 to 2\u00b792), had an increased 30-day in-hospital mortality rate. Postoperative mortality also increased with stroke-related co-morbidities, and with stroke 1\u20136 months before surgery (RR 3\u00b731, 2\u00b791 to 3\u00b775).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Patients with previous stroke had a higher risk of adverse postoperative outcomes; their 30-day in-hospital mortality rate was nearly twice that of patients without previous stroke.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.9639","type":"journal-article","created":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T09:06:15Z","timestamp":1410858375000},"page":"1616-1622","source":"Crossref","is-referenced-by-count":29,"title":["Outcomes after surgery in patients with previous stroke"],"prefix":"10.1093","volume":"101","author":[{"given":"C C","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Health Policy Research Centre, Taipei Medical University Hospital, Taipei, Taiwan"},{"name":"Health Policy Research Centre, Taipei Medical University Hospital, Taipei, Taiwan"},{"name":"School of Medicine, Taipei Medical University, Taipei, Taiwan"},{"name":"Department of School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P Y","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Eldercare, National Tainan Institute of Nursing, Tainan City, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C C","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Surgery, China Medical University Hospital, Taichung, Taiwan"},{"name":"Department of Surgery, University of Illinois, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C J","family":"Hu","sequence":"additional","affiliation":[{"name":"School of Medicine, Taipei Medical University, Taipei, Taiwan"},{"name":"Department of Neurology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C H","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Medicine, Taipei Medical University, Taipei, Taiwan"},{"name":"Department of Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T L","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Health Policy Research Centre, Taipei Medical University Hospital, Taipei, Taiwan"},{"name":"Health Policy Research Centre, Taipei Medical University Hospital, Taipei, Taiwan"},{"name":"School of Medicine, Taipei Medical University, Taipei, 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