{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:16:43Z","timestamp":1792268203304,"version":"4.4.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"National R&D Program for Cancer Control funded by the Ministry of Health & Welfare, Republic of Korea","award":["No. 1120310"],"award-info":[{"award-number":["No. 1120310"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The fate of the portal vein (PV) after pancreatoduodenectomy, especially its long-term patency and associated complications, has received little attention. The aim of this study was to explore the long-term patency rate of the PV after pancreatoduodenectomy, focusing on risk factors for PV stenosis\/occlusion and associated complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Serial CT images of patients who underwent pancreatoduodenectomy for periampullary cancer between January 2000 and June 2012 in a single institution were evaluated for PV stenosis or occlusion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 826 patients were enrolled. The PV stenosis\/occlusion rate after pancreatoduodenectomy was 19\u00b76 per cent and the 5-year patency rate 69\u00b79 per cent. The most frequent cause of PV stenosis\/occlusion was local recurrence followed by postoperative change and PV thrombosis. Patients who underwent PV resection had a higher PV stenosis\/occlusion rate than those who did not (51 versus 17\u00b74 per cent; P &amp;lt; 0\u00b7001). The 3-year patency rate was highest in patients with cancer of the ampulla of Vater and lowest in patients with pancreatic cancer (91\u00b79 versus 55\u00b75 per cent respectively; P &amp;lt; 0\u00b7001). Multivariable analysis showed that risk factors for PV stenosis\/occlusion included primary tumour location, chemoradiotherapy and PV resection. PV stenosis or occlusion without disease recurrence was observed in 17\u00b73 per cent of the patients. PV resection and grade B or C pancreatic fistula were independent risk factors for PV stenosis\/occlusion. Among 162 patients with PV stenosis or occlusion, five (3\u00b71 per cent) had fatal recurrent gastrointestinal bleeding.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>PV stenosis or occlusion is common after pancreatoduodenectomy, particularly if the PV has been resected and\/or chemoradiotherapy was given after surgery. Although recurrence is the most frequent cause of PV stenosis\/occlusion, this complication is found in a significant proportion of patients without disease recurrence.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.9682","type":"journal-article","created":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T16:20:09Z","timestamp":1415809209000},"page":"77-84","source":"Crossref","is-referenced-by-count":61,"title":["Portal vein patency after pancreatoduodenectomy for periampullary cancer"],"prefix":"10.1093","volume":"102","author":[{"given":"M J","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine , Seoul,","place":["Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J-Y","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine , Seoul,","place":["Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y R","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine , Seoul,","place":["Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine , Seoul,","place":["Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S-W","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine , 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