{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:40:20Z","timestamp":1791819620478,"version":"4.3.4"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T00:00:00Z","timestamp":1613952000000},"content-version":"vor","delay-in-days":2070,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","award":["07\/37\/64"],"award-info":[{"award-number":["07\/37\/64"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"name":"French Ministry of Health"},{"name":"Netherlands Heart Foundation","award":["2002\/B197"],"award-info":[{"award-number":["2002\/B197"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The benefits of endovascular repair of ruptured abdominal aortic aneurysm remain controversial, without any strong evidence about advantages in specific subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An individual-patient data meta-analysis of three recent randomized trials of endovascular versus open repair of abdominal aortic aneurysm was conducted according to a prespecified analysis plan, reporting on results to 90 days after the index event.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The trials included a total of 836 patients. The mortality rate across the three trials was 31\u00b73 per cent for patients randomized to endovascular repair\/strategy and 34\u00b70 per cent for those randomized to open repair at 30 days (pooled odds ratio 0\u00b788, 95 per cent c.i. 0\u00b766 to 1\u00b718), and 34\u00b73 and 38\u00b70 per cent respectively at 90 days (pooled odds ratio 0\u00b785, 0\u00b764 to 1\u00b713). There was no evidence of significant heterogeneity in the odds ratios between trials. Mean(s.d.) aneurysm diameter was 8\u00b72(1\u00b79) cm and the overall in-hospital mortality rate was 34\u00b78 per cent. There was no significant effect modification with age or Hardman index, but there was indication of an early benefit from an endovascular strategy for women. Discharge from the primary hospital was faster after endovascular repair (hazard ratio 1\u00b724, 95 per cent c.i. 1\u00b704 to 1\u00b747). For open repair, 30-day mortality diminished with increasing aneurysm neck length (adjusted odds ratio 0\u00b769 (95 per cent c.i. 0\u00b753 to 0\u00b789) per 15 mm), but aortic diameter was not associated with mortality for either type of repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Survival to 90 days following an endovascular or open repair strategy is similar for all patients and for the restricted population anatomically suitable for endovascular repair. Women may benefit more from an endovascular strategy than men and patients are, on average, discharged sooner after endovascular repair.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bjs.9852","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T05:13:41Z","timestamp":1435122821000},"page":"1229-1239","source":"Crossref","is-referenced-by-count":97,"title":["Individual-patient meta-analysis of three randomized trials comparing endovascular\n                    <i>versus<\/i>\n                    open repair for ruptured abdominal aortic aneurysm"],"prefix":"10.1093","volume":"102","author":[{"given":"M J","family":"Sweeting","sequence":"first","affiliation":[{"name":"Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Balm","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Academic Medical Centre, 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