{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:58:24Z","timestamp":1790855904326,"version":"4.1.0"},"reference-count":23,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJS Open"],"DOI":"10.1002\/bjs5.50160","type":"journal-article","created":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T23:37:29Z","timestamp":1553038649000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Randomized clinical trial of prophylactic transanal irrigation<i>versus<\/i>supportive therapy to prevent symptoms of low anterior resection syndrome after rectal resection"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4211-6728","authenticated-orcid":false,"given":"H. R.","family":"Rosen","sequence":"first","affiliation":[{"name":"Faculty of Surgical Oncology, Sigmund Freud University Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Kneist","sequence":"additional","affiliation":[{"name":"Department of General, Visceral and Transplantation Surgery, Johannes Gutenberg University Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"F\u00fcrst","sequence":"additional","affiliation":[{"name":"Department of Surgery, Caritas\u2010Hospital St Josef Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Kr\u00e4mer","sequence":"additional","affiliation":[{"name":"Department of Surgery, Caritas\u2010Hospital St Josef Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Hebenstreit","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital St John of God Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. F.","family":"Schiemer","sequence":"additional","affiliation":[{"name":"Department of General, Visceral and Transplantation Surgery, Johannes Gutenberg University Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,3,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S0039-6060(97)90087-8","article-title":"Chances of cure are not compromised with sphincter\u2010saving procedures for cancer of the lower third of the rectum","volume":"122","author":"Lavery IC","year":"1997","journal-title":"Surgery"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/DCR.0b013e31827c4a8c","article-title":"Low rectal cancer: classification and standardization of surgery","volume":"56","author":"Rullier E","year":"2013","journal-title":"Dis Colon Rectum"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00000658-198308000-00008","article-title":"The relationship between the extent of distal clearance and survival and local recurrence rates after curative anterior resection for carcinoma of the rectum","volume":"198","author":"Pollett WG","year":"1983","journal-title":"Ann Surg"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/bjs.1800700305","article-title":"Reappraisal of the 5 centimetre rule of distal excision for carcinoma of the rectum: a study of distal intramural spread and of patients' survival","volume":"70","author":"Williams NS","year":"1983","journal-title":"Br J Surg"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1055\/s-0037-1606114","article-title":"Intersphincteric resection pushing the envelope for sphincter preservation","volume":"30","author":"Denost Q","year":"2017","journal-title":"Clin Colon Rectal Surg"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"e403","DOI":"10.1016\/S1470-2045(12)70236-X","article-title":"Anterior resection syndrome","volume":"13","author":"Bryant CL","year":"2012","journal-title":"Lancet Oncol"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1111\/j.1463-1318.2006.00992.x","article-title":"Low anterior resection with total mesorectal excision for rectal cancer: functional assessment and factors affecting outcome","volume":"8","author":"Kakodkar R","year":"2006","journal-title":"Colorectal Dis"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00384-017-2765-0","article-title":"Functional outcome following rectal surgery\u00a0\u2013\u00a0predisposing factors for low anterior resection syndrome","volume":"32","author":"Hughes DL","year":"2017","journal-title":"Int J Colorectal Dis"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/codi.13767","article-title":"Defining low anterior resection syndrome: a systematic review of the literature","volume":"19","author":"Keane C","year":"2017","journal-title":"Colorectal Dis"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1097\/SLA.0b013e31824f1c21","article-title":"Low anterior resection syndrome score: development and validation of a symptom\u2010based scoring system for bowel dysfunction after low anterior resection for rectal cancer","volume":"255","author":"Emmertsen KJ","year":"2012","journal-title":"Ann Surg"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1097\/SLA.0b013e31828fac0b","article-title":"International validation of the low anterior resection syndrome score","volume":"259","author":"Juul T","year":"2014","journal-title":"Ann Surg"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"e335","DOI":"10.1111\/j.1463-1318.2011.02692.x","article-title":"Transanal irrigation improves quality of life in patients with low anterior resection syndrome","volume":"13","author":"Rosen H","year":"2011","journal-title":"Colorectal Dis"},{"key":"e_1_2_6_14_1","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1007\/s00384-009-0719-x","article-title":"Retrograde colonic irrigation for faecal incontinence after low anterior resection","volume":"24","author":"Koch SM","year":"2009","journal-title":"Int J Colorectal Dis"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF02050307","article-title":"Etiology and management of fecal incontinence","volume":"36","author":"Jorge JM","year":"1993","journal-title":"Dis Colon Rectum"},{"key":"e_1_2_6_16_1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1136\/bmj.305.6846.160","article-title":"Validating the SF\u201036 health survey questionnaire: new outcome measure for primary care","volume":"305","author":"Brazier JE","year":"1992","journal-title":"BMJ"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF02471596","article-title":"Self washout method for defecational complaints following low anterior rectal resection","volume":"19","author":"Iwama T","year":"1989","journal-title":"Jpn J Surg"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00384-017-2954-x","article-title":"Treatment possibilities for low anterior resection syndrome: a review of the literature","volume":"33","author":"Dulskas A","year":"2018","journal-title":"Int J Colorectal Dis"},{"key":"e_1_2_6_19_1","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/s10151-018-1829-7","article-title":"Role of transanal irrigation in the treatment of anterior resection syndrome","volume":"22","author":"Martellucci J","year":"2018","journal-title":"Tech Coloproctol"},{"key":"e_1_2_6_20_1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1097\/DCR.0000000000001089","article-title":"Antegrade enema after total mesorectal excision for rectal cancer: the last chance to avoid definitive colostomy for refractory low anterior resection syndrome and fecal incontinence","volume":"61","author":"Didailler R","year":"2018","journal-title":"Dis Colon Rectum"},{"key":"e_1_2_6_21_1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/SLA.0b013e3181485617","article-title":"A randomized multicenter trial to compare long\u2010term functional outcome, quality of life, and complications of surgical procedures for low rectal cancers","volume":"246","author":"Fazio VW","year":"2007","journal-title":"Ann Surg"},{"key":"e_1_2_6_22_1","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.surg.2008.03.014","article-title":"Surgical autonomic denervation results in altered colonic motility: an explanation for low anterior resection syndrome?","volume":"143","author":"Lee WY","year":"2008","journal-title":"Surgery"},{"key":"e_1_2_6_23_1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s10151-015-1400-8","article-title":"Global audit on bowel perforations related to transanal irrigation","volume":"20","author":"Christensen P","year":"2016","journal-title":"Tech Coloproctol"},{"key":"e_1_2_6_24_1","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.3748\/wjg.v23.i11.2029","article-title":"Predictive factors for compliance with transanal irrigation for the treatment of defecation disorders","volume":"23","author":"Bildstein C","year":"2017","journal-title":"World J Gastroenterol"}],"container-title":["BJS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs5.50160","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bjs5.50160","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bjs5.50160","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bjs5.50160","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:42:36Z","timestamp":1663116156000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjsopen\/article\/3\/4\/461-465\/6060839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,18]]},"references-count":23,"alternative-id":["10.1002\/bjs5.50160"],"URL":"https:\/\/doi.org\/10.1002\/bjs5.50160","archive":["Portico"],"relation":{},"ISSN":["2474-9842","2474-9842"],"issn-type":[{"value":"2474-9842","type":"print"},{"value":"2474-9842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,18]]},"article-number":"bjs5.50160"}}